# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3292697 | F | Cytotoxicity against human HL60 cells assessed as inhibition of proliferation after 48 hrs by MTT assay | Homo sapiens | 7 | ALA3286196 | cell-based format | Scientific Literature | |
2. | ALA3296163 | F | Cytotoxicity against human HL60 cells assessed as inhibition of proliferation after 72 hrs by MTT assay | Homo sapiens | 7 | ALA3286196 | cell-based format | Scientific Literature | |
3. | ALA3296164 | F | Cytotoxicity against human SSMC-7721 cells assessed as inhibition of proliferation after 48 hrs by MTT assay | Homo sapiens | 7 | ALA3286196 | cell-based format | Scientific Literature | |
4. | ALA3296165 | F | Cytotoxicity against human HeLa cells assessed as inhibition of proliferation after 48 hrs by MTT assay | Homo sapiens | 7 | ALA3286196 | cell-based format | Scientific Literature | |
5. | ALA3296166 | F | Cytotoxicity against human HepG2 cells assessed as inhibition of proliferation after 48 hrs by MTT assay | Homo sapiens | 7 | ALA3286196 | cell-based format | Scientific Literature | |
6. | ALA3296167 | A | Cytotoxicity against human L02 cells assessed as cell viability after 48 hrs by MTT assay | Homo sapiens | 1 | ALA3286196 | cell-based format | Scientific Literature | |
7. | ALA3296168 | A | Cytotoxicity against human HEK293T cells assessed as cell viability after 48 hrs by MTT assay | Homo sapiens | 1 | ALA3286196 | cell-based format | Scientific Literature | |
8. | ALA3296169 | B | Inhibition of NADPH-reduced rat recombinant wild type TrxR after 30 mins by DTNB assay | Rattus norvegicus | 1 | ALA3286196 | assay format | Scientific Literature | |
9. | ALA3296170 | B | Inhibition of NADPH-reduced rat recombinant TrxR1 U498C mutant after 30 mins by DTNB assay | Rattus norvegicus | 1 | ALA3286196 | assay format | Scientific Literature | |
10. | ALA3296171 | B | Inhibition of rat recombinant glutathione reductase after 30 mins by DTNB assay | Rattus norvegicus | 1 | ALA3286196 | single protein format | Scientific Literature | |
11. | ALA3296172 | B | Inhibition of glutathione peroxidase (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3286196 | assay format | Scientific Literature | |
12. | ALA3296175 | B | Inhibition of NADPH-reduced rat recombinant wild type TrxR at 40 nM after 30 mins by DTNB assay in presence of 1 mM GSH | Rattus norvegicus | 1 | ALA3286196 | assay format | Scientific Literature | |
13. | ALA3296176 | B | Inhibition of human TrxR activity in human HeLa cell lysate after 12 hrs by insulin reduction assay | Homo sapiens | 2 | ALA3286196 | cell-based format | Scientific Literature | |
14. | ALA3296177 | B | Inhibition of human TrxR activity in living human HeLa cells after 4 hrs by TRFS-green based fluorescence microscopy imaging | Homo sapiens | 1 | ALA3286196 | cell-based format | Scientific Literature | |
15. | ALA3296178 | B | Binding affinity to TrxR activity in human HeLa cell lysate after 30 mins incubation by pulldown/Western blotting analysis | Homo sapiens | 1 | ALA3286196 | cell-based format | Scientific Literature | |
16. | ALA3296179 | F | Induction of TrxR protein expression in human HeLa cells at 2 uM after 12 hrs by Western blotting analysis | Homo sapiens | 1 | ALA3286196 | cell-based format | Scientific Literature | |
17. | ALA3296180 | F | Reduction in cellular GSH in human HL60 cells assessed as intracellular GSH at 100 uM after 24 hrs relative to control | Homo sapiens | 1 | ALA3286196 | cell-based format | Scientific Literature | |
18. | ALA3296181 | F | Cytotoxicity against HEK cells expressing IRES at 2 to 5 uM after 48 hrs by MTT assay | Homo sapiens | 1 | ALA3286196 | cell-based format | Scientific Literature | |
19. | ALA3296182 | F | Cytotoxicity against HEK cells expressing TrxR1 at 2 to 5 uM after 48 hrs by MTT assay | Homo sapiens | 1 | ALA3286196 | cell-based format | Scientific Literature | |
20. | ALA3296183 | F | Induction of TrxR protein expression in human HeLa cells at 1 uM after 24 hrs by Western blotting analysis | Homo sapiens | 1 | ALA3286196 | cell-based format | Scientific Literature |