# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3300177 | B | Inhibition of Staphylococcus aureus TMK assessed as decrease in ATP production using dTDP and ADP as substrate after 3.5 hrs by luciferin/luciferase based luminescence analysis | Staphylococcus aureus | 29 | assay format | Scientific Literature | ||
2. | ALA3300178 | P | Retention time of the compound by LC-MS method | 29 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA3300179 | F | Antibacterial activity against Staphylococcus aureus ARC 516 assessed as growth inhibition by broth microdilution method | Staphylococcus aureus | 18 | organism-based format | Scientific Literature | ||
4. | ALA3300180 | F | Antibacterial activity against methicillin-resistant and quinolone-resistant Staphylococcus aureus ARC 517 assessed as growth inhibition by broth microdilution method | Staphylococcus aureus | 18 | organism-based format | Scientific Literature | ||
5. | ALA3300181 | P | Octanol-sodium phosphate buffer partition coefficient, log D of the compound at pH 7.4 by shake-flask method | 17 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA3300182 | A | Fraction unbound in human plasma at 10 uM after 5 hrs by rapid equilibrium dialysis method | Homo sapiens | 11 | cell-free format | Scientific Literature | ||
7. | ALA3300183 | A | Fraction unbound in mouse plasma at 10 uM after 5 hrs by rapid equilibrium dialysis method | Mus musculus | 11 | cell-free format | Scientific Literature | ||
8. | ALA3300184 | A | In vivo clearance in Wistar rat at 5 to 10 mg/kg, iv administered as bolus dose | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
9. | ALA3300185 | F | Antibacterial activity against Streptococcus pneumoniae ARC 2481 assessed as growth inhibition by broth microdilution method | Streptococcus pneumoniae | 4 | organism-based format | Scientific Literature | ||
10. | ALA3300443 | F | Antibacterial activity against Streptococcus pyogenes ARC 2834 assessed as growth inhibition by broth microdilution method | Streptococcus pyogenes | 4 | organism-based format | Scientific Literature | ||
11. | ALA3300444 | F | Antibacterial activity against Staphylococcus epidermidis ARC 323 assessed as growth inhibition by broth microdilution method | Staphylococcus epidermidis | 4 | organism-based format | Scientific Literature | ||
12. | ALA3300445 | F | Antibacterial activity against linezolid-resistant Enterococcus faecium ARC 1239 assessed as growth inhibition by broth microdilution method | Enterococcus faecium | 4 | organism-based format | Scientific Literature | ||
13. | ALA3300446 | F | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ARC 1618 assessed as growth inhibition by broth microdilution method | Enterococcus faecalis | 4 | organism-based format | Scientific Literature | ||
14. | ALA3300447 | F | Antibacterial activity against Escherichia coli ARC 523 assessed as growth inhibition by broth microdilution method | Escherichia coli | 4 | organism-based format | Scientific Literature | ||
15. | ALA3300448 | F | Antibacterial activity against Pseudomonas aeruginosa ARC 545 assessed as growth inhibition by broth microdilution method | Pseudomonas aeruginosa | 4 | organism-based format | Scientific Literature | ||
16. | ALA3300449 | B | Inhibition of human thymidine kinase assessed as ATP production by measuring Escherichia coli DdlA-catalyzed inorganic phosphate production using dTDP and ADP as substrate by malachite green reagent based assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
17. | ALA3300450 | B | Ratio of IC50 for human thymidine kinase to IC50 for Staphylococcus aureus TMK | 4 | assay format | Scientific Literature | |||
18. | ALA3300456 | A | Cytotoxicity against human A549 cells | Homo sapiens | 4 | cell-based format | Scientific Literature |