Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by microplate reader analysis
Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate at 10 uM after 10 mins by microplate reader analysis
Inhibition of Brugia malayi chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate at 10 uM after 10 mins by microplate reader analysis
Inhibition of Entamoeba histolytica chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate at 10 uM after 10 mins by microplate reader analysis
Inhibition of Plasmodium falciparum chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate at 10 uM after 10 mins by microplate reader analysis
Protonophoric activity in human HEK293T/17 cells assessed as mitochondrial membrane depolarization at 50 uM for 30 mins by TMRE dye based fluorescence spectrometry
Protonophoric activity in human HEK293T/17 cells assessed as mitochondrial membrane depolarization at 50 uM for 30 mins by TMRE dye based flow cytometry
Antiparasitic activity against Onchocerca volvulus assessed as inhibition of L3 to L4 larval molting at 10 uM for 24 hrs measured until 6 days by using inverted microscopic analysis in presence of PBMC
Antiparasitic activity against Onchocerca volvulus assessed as inhibition of L3 to L4 larval molting at 1 uM for 24 hrs measured until 6 days by using inverted microscopic analysis in presence of PBMC
Antiparasitic activity against Onchocerca volvulus assessed as inhibition of L3 to L4 larval molting at 100 uM for 24 hrs measured until 6 days by using inverted microscopic analysis in presence of PBMC
Antiparasitic activity against Onchocerca volvulus assessed as inhibition of L3 to L4 larval molting at 0.5 uM for 24 hrs measured until 6 days by using inverted microscopic analysis in presence of PBMC and 0.5 uM protonophore CCCP
Antiparasitic activity against Onchocerca volvulus assessed as inhibition of L3 to L4 larval molting at 1 uM for 24 hrs measured until 6 days by using inverted microscopic analysis in presence of PBMC and 1 uM protonophore CCCP
Antiparasitic activity against Onchocerca volvulus assessed as inhibition of L3 to L4 larval molting at 2.5 uM for 24 hrs measured until 6 days by using inverted microscopic analysis in presence of PBMC and 2.5 uM protonophore CCCP