| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3380548 | B | Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 mins | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 2. | ALA3380549 | B | Inhibition of ITK in human Jurkat cells assessed as reduction in PLC-gamma phosphorylation after 30 mins | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 3. | ALA3380550 | B | Inhibition of human His-tagged full length AURKA using kemptide peptide as substrate after 60 mins | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 4. | ALA3380551 | B | Selectivity ratio of Ki for human His-tagged full length AURKAto Ki for GST-tagged full length ITK (unknown origin) | Homo sapiens | 22 | assay format | Scientific Literature | ||
| 5. | ALA3380552 | P | Kinetic solubility of the compound in PBS buffer at 10 mM at pH 7.4 after 24 hrs by HPLC analysis | 23 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA3380553 | P | Lipophilicity, log D of the compound in 1-octanol/phosphate buffer at 10 mM at pH 7.4 after 20 mins by UPLC/MS/MS analysis | 23 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA3380554 | A | Apparent permeability across MDCK cells | Canis lupus familiaris | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA3380555 | B | Inhibition of CLK2 (unknown origin) at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3380556 | B | Inhibition of FLT3 (unknown origin) at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3380557 | B | Inhibition of FLT3 D835Y mutant (unknown origin) at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3380558 | B | Inhibition of TRKA (unknown origin) at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3380559 | B | Inhibition of TRKB (unknown origin) at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA3380560 | B | Inhibition of TRKC (unknown origin) at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA3380561 | A | Clearance in human hepatocytes | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA3371426 | A | Plasma protein binding in human | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
| 16. | ALA3371427 | A | Cmax in BALB/c mouse at 50 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA3371428 | A | AUC in BALB/c mouse at 1 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA3371429 | A | AUC in BALB/c mouse at 50 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3371430 | A | Clearance in BALB/c mouse at 1 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3371431 | A | Half life in BALB/c mouse at 1 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature |
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