#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3428281	Binding	Inhibition of ITK in TCR stimulated human Jurkat T cells assessed as reduction of PLC-gamma phosphorylation preincubated for 30 mins followed by TCR induction for 2 mins	Homo sapiens	13	ALA3425442	cell-based format	Scientific Literature
2.	ALA3428282	ADME	Cytotoxicity against human Jurkat T cells without TCR stimulation assessed as cell viability by ATPlite assay	Homo sapiens	10	ALA3425442	cell-based format	Scientific Literature
3.	ALA3428283	Binding	Inhibition of LCK (unknown origin)	Homo sapiens	13	ALA3425442	single protein format	Scientific Literature
4.	ALA3428426	Binding	Selectivity ratio of Ki for LCK (unknown origin) to Ki for GST-tagged recombinant full length human ITK	Homo sapiens	13	ALA3425442	assay format	Scientific Literature
5.	ALA3428428	ADME	Selectivity ratio of IC50 for human Jurkat T cells without TCR stimulation to IC50 for ITK in TCR stimulated human Jurkat T cells assessed as reduction of PLC-gamma phosphorylation	Homo sapiens	4	ALA3425442	cell-based format	Scientific Literature
6.	ALA3428433	Binding	Inhibition of human ERG at 10 uM by patch clamp assay relative to control	Homo sapiens	4	ALA3425442	assay format	Scientific Literature
7.	ALA3428434	ADME	Cytotoxicity against hepatocytes (unknown origin)	Not specified	4	ALA3425442	cell-based format	Scientific Literature
8.	ALA3429289	Binding	Binding affinity to human 5HT-2A receptor assessed as protein-compound complex at 10 uM relative to control	Homo sapiens	1	ALA3425442	single protein format	Scientific Literature
9.	ALA3429290	Binding	Binding affinity to human dopamine D1 receptor assessed as protein-compound complex at 10 uM relative to control	Homo sapiens	1	ALA3425442	single protein format	Scientific Literature
10.	ALA3429291	Binding	Binding affinity to human dopamine D2S receptor assessed as protein-compound complex at 10 uM relative to control	Homo sapiens	1	ALA3425442	single protein format	Scientific Literature
11.	ALA3429292	Binding	Binding affinity to human 5-HT transporter assessed as protein-compound complex at 10 uM relative to control	Homo sapiens	1	ALA3425442	single protein format	Scientific Literature
12.	ALA3429293	Binding	Binding affinity to L-type calcium channel verapamil binding site (unknown origin) assessed as protein-compound complex at 10 uM relative to control	Homo sapiens	1	ALA3425442	assay format	Scientific Literature
13.	ALA3380548	Binding	Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 mins	Homo sapiens	23	ALA3297697	single protein format	Scientific Literature
14.	ALA3380549	Binding	Inhibition of ITK in human Jurkat cells assessed as reduction in PLC-gamma phosphorylation after 30 mins	Homo sapiens	16	ALA3297697	cell-based format	Scientific Literature
15.	ALA3380550	Binding	Inhibition of human His-tagged full length AURKA using kemptide peptide as substrate after 60 mins	Homo sapiens	22	ALA3297697	single protein format	Scientific Literature
16.	ALA3380551	Binding	Selectivity ratio of Ki for human His-tagged full length AURKAto Ki for GST-tagged full length ITK (unknown origin)	Homo sapiens	22	ALA3297697	assay format	Scientific Literature
17.	ALA3380552	Physicochemical	Kinetic solubility of the compound in PBS buffer at 10 mM at pH 7.4 after 24 hrs by HPLC analysis		23	ALA3297697	small-molecule physicochemical format	Scientific Literature
18.	ALA3380553	Physicochemical	Lipophilicity, log D of the compound in 1-octanol/phosphate buffer at 10 mM at pH 7.4 after 20 mins by UPLC/MS/MS analysis		23	ALA3297697	small-molecule physicochemical format	Scientific Literature
19.	ALA3380554	ADME	Apparent permeability across MDCK cells	Canis lupus familiaris	7	ALA3297697	cell-based format	Scientific Literature
20.	ALA3380555	Binding	Inhibition of CLK2 (unknown origin) at 0.1 uM	Homo sapiens	1	ALA3297697	single protein format	Scientific Literature