# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3300366 | F | Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins | Homo sapiens | 16 | ALA3297663 | cell-based format | Scientific Literature | |
2. | ALA3300369 | F | Agonist activity at human HCA3 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation at 50 uM after 30 mins | Homo sapiens | 20 | ALA3297663 | cell-based format | Scientific Literature | |
3. | ALA3300372 | F | Agonist activity at human HCA1 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation up to 50 uM after 30 mins | Homo sapiens | 14 | ALA3297663 | cell-based format | Scientific Literature | |
4. | ALA3300463 | F | Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins pre-incubated in presence of 5% BSA | Homo sapiens | 6 | ALA3297663 | cell-based format | Scientific Literature | |
5. | ALA4056812 | F | Agonist activity at recombinant human HCA2 receptor expressed in Flp-IN HEK cells assessed as reduction in forskolin-stimulated cAMP accumulation measured after 30 mins | Homo sapiens | 24 | ALA4052730 | cell-based format | Scientific Literature | |
6. | ALA4056813 | B | Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting method | Homo sapiens | 24 | ALA4052730 | cell-based format | Scientific Literature | |
7. | ALA4056814 | F | Agonist activity at recombinant human HCA2 receptor expressed in Flp-IN HEK cells assessed as reduction in forskolin-stimulated cAMP accumulation measured after 30 mins relative to control | Homo sapiens | 24 | ALA4052730 | cell-based format | Scientific Literature |