# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3374988 | B | Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells | Rattus norvegicus | 41 | ALA3351812 | cell-based format | Scientific Literature | |
2. | ALA3374989 | B | Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells relative to glutamate | Rattus norvegicus | 40 | ALA3351812 | cell-based format | Scientific Literature | |
3. | ALA3374990 | B | Positive allosteric modulation of rat mGlu1 receptor | Rattus norvegicus | 1 | ALA3351812 | single protein format | Scientific Literature | |
4. | ALA3374991 | B | Positive allosteric modulation of rat mGlu2 receptor | Rattus norvegicus | 1 | ALA3351812 | single protein format | Scientific Literature | |
5. | ALA3374992 | B | Positive allosteric modulation of rat mGlu3 receptor | Rattus norvegicus | 1 | ALA3351812 | single protein format | Scientific Literature | |
6. | ALA3374993 | B | Positive allosteric modulation of rat mGlu6 receptor | Rattus norvegicus | 1 | ALA3351812 | single protein format | Scientific Literature | |
7. | ALA3374994 | B | Positive allosteric modulation of rat mGlu7 receptor | Rattus norvegicus | 1 | ALA3351812 | single protein format | Scientific Literature | |
8. | ALA3374995 | B | Positive allosteric modulation of rat mGlu8 receptor | Rattus norvegicus | 1 | ALA3351812 | single protein format | Scientific Literature | |
9. | ALA3374996 | B | Positive allosteric modulation of human mGlu1 receptor | Homo sapiens | 1 | ALA3351812 | single protein format | Scientific Literature | |
10. | ALA3374997 | B | Positive allosteric modulation of human mGlu2 receptor | Homo sapiens | 1 | ALA3351812 | single protein format | Scientific Literature | |
11. | ALA3374998 | B | Positive allosteric modulation of human mGlu3 receptor | Homo sapiens | 1 | ALA3351812 | single protein format | Scientific Literature | |
12. | ALA3374999 | B | Positive allosteric modulation of human mGlu6 receptor | Homo sapiens | 1 | ALA3351812 | single protein format | Scientific Literature | |
13. | ALA3375000 | B | Positive allosteric modulation of human mGlu7 receptor | Homo sapiens | 1 | ALA3351812 | single protein format | Scientific Literature | |
14. | ALA3375001 | B | Positive allosteric modulation of human mGlu8 receptor | Homo sapiens | 1 | ALA3351812 | single protein format | Scientific Literature | |
15. | ALA3375002 | A | Fraction unbound in rat plasma | Rattus norvegicus | 4 | ALA3351812 | cell-free format | Scientific Literature | |
16. | ALA3375003 | A | Fraction unbound in human plasma | Homo sapiens | 4 | ALA3351812 | cell-free format | Scientific Literature | |
17. | ALA3375004 | A | Stability in rat plasma at 37 degC after 4 hrs | Rattus norvegicus | 1 | ALA3351812 | cell-free format | Scientific Literature | |
18. | ALA3375005 | A | Stability in human plasma at 37 degC after 4 hrs | Homo sapiens | 1 | ALA3351812 | cell-free format | Scientific Literature | |
19. | ALA3378085 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 2 | ALA3351812 | single protein format | Scientific Literature | |
20. | ALA3378086 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA3351812 | single protein format | Scientific Literature |