# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3368372 | B | Agonist activity at human RXR-alpha expressed in HEK293 cells coexpressing with pCMX-beta-gal after 24 to 48 hrs by luciferase reporter gene assay | Homo sapiens | 6 | ALA3351942 | cell-based format | Scientific Literature | |
2. | ALA3368373 | B | Agonist activity at human RXR-alpha expressed in HEK293 cells coexpressing with pCMX-beta-gal at 10 uM after 24 to 48 hrs by luciferase reporter gene assay in presence of PA452 pan-antagonist | Homo sapiens | 2 | ALA3351942 | cell-based format | Scientific Literature | |
3. | ALA3368375 | B | Activation of human RAR-alpha expressed in HEK293 cells coexpressing with tk-betaRE-Luc after 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA3351942 | cell-based format | Scientific Literature | |
4. | ALA3368376 | B | Activation of human LXR-alpha expressed in HEK293 cells coexpressing with pGL4.1-DR4-Luc after 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA3351942 | cell-based format | Scientific Literature | |
5. | ALA3368377 | B | Activation of RXR/LXR heterodimer in mouse RAW264.7 cells assessed as increase in ABCA1 mRNA level at 10 uM by quantitative RT-PCR analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
6. | ALA3368379 | B | Activation of RXR/LXR heterodimer in mouse RAW264.7 cells assessed as potentiation of T0901317-induced increase in ABCA1 mRNA level at 10 uM by quantitative RT-PCR analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
7. | ALA3368381 | B | Activation of PPARgamma/RXR heterodimer in human hepatoma cells assessed as increase in ANGPTL4 mRNA level at 10 uM by quantitative RT-PCR analysis | Homo sapiens | 2 | ALA3351942 | cell-based format | Scientific Literature | |
8. | ALA3368382 | B | Activation of PPARgamma/RXR heterodimer in human hepatoma cells assessed as potentiation of rosiglitazone-induced increase in ANGPTL4 mRNA level at 10 uM by quantitative RT-PCR analysis | Homo sapiens | 2 | ALA3351942 | cell-based format | Scientific Literature | |
9. | ALA3368383 | B | Activation of RAR/RXR heterodimer in mouse F9 cells assessed as increase in CYP26A1 mRNA level at 10 uM by quantitative RT-PCR analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
10. | ALA3368385 | B | Activation of RAR/RXR heterodimer in mouse F9 cells assessed as increase in CYP26A1 mRNA level at 10 uM by quantitative RT-PCR analysis in presence of atRA | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
11. | ALA3368603 | B | Activation of RXR/VDR heterodimer in human hepatoma cells assessed as increase in CYP24A1 mRNA level at 10 uM by quantitative RT-PCR analysis | Homo sapiens | 2 | ALA3351942 | cell-based format | Scientific Literature | |
12. | ALA3368605 | B | Activation of RXR/VDR heterodimer in human hepatoma cells assessed as increase in CYP24A1 mRNA level at 10 uM in presence of VDR agonist calcitriol by quantitative RT-PCR analysis | Homo sapiens | 2 | ALA3351942 | cell-based format | Scientific Literature | |
13. | ALA3368606 | B | Activation of RXR/LXR heterodimer in mouse RAW264.7 cells assessed as increase in ABCA1 protein level at 10 uM after 24 hrs by Western blotting analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
14. | ALA3368607 | B | Activation of PPARgamma/RXR heterodimer in mouse 3T3-L1 cell assessed as induction of adipogenesis at 10 uM after 6 days by Oil red O-staining | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
15. | ALA3368611 | B | Activation of LXR in mouse C2C12 cells assessed as induction of SREBP1 mRNA expression at 10 uM after 24 hrs by quantitative RT-PCR analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
16. | ALA3368612 | B | Activation of LXR in mouse C2C12 cells assessed as induction of ApoD mRNA expression at 10 uM after 24 hrs by quantitative RT-PCR analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
17. | ALA3368613 | B | Activation of LXR in mouse C2C12 cells assessed as induction of ABCA1 mRNA expression at 10 uM after 24 hrs by quantitative RT-PCR analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
18. | ALA3368614 | B | Activation of LXR in mouse C2C12 cells assessed as induction of ApoE mRNA expression at 10 uM after 24 hrs by quantitative RT-PCR analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
19. | ALA3368615 | B | Activation of LXR in mouse C2C12 cells assessed as induction of LPL mRNA expression at 10 uM after 24 hrs by quantitative RT-PCR analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature | |
20. | ALA3368616 | B | Activation of LXR in mouse C2C12 cells assessed as induction of ABCA1 mRNA expression at 10 uM after 24 hrs in presence of T0901317 by quantitative RT-PCR analysis | Mus musculus | 2 | ALA3351942 | cell-based format | Scientific Literature |