# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3372666 | F | Antihyperproliferative activity against human HaCaT cells assessed as inhibition of cell growth after 48 hrs by phase contrast microscopy | Homo sapiens | 74 | ALA3351891 | cell-based format | Scientific Literature | |
2. | ALA3372668 | P | Induction of superoxide generation measured per 2 mU of enzyme in presence of cytochrome P450 oxidoreductase | 4 | ALA3351891 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA3372669 | P | Induction of superoxide generation measured per U of enzyme in presence of NQO-1 | 4 | ALA3351891 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA3372670 | F | Induction of superoxide generation in human HaCaT cells assessed as mean fluorescence intensity at 50 umol/L for 30 mins acute treatment (Rvb = 7.1 +/- 5.2 no unit) | Homo sapiens | 4 | ALA3351891 | cell-based format | Scientific Literature | |
5. | ALA3372671 | F | Induction of superoxide generation in human HaCaT cells assessed as mean fluorescence intensity at 5 umol/L for 18 hrs chronic treatment (Rvb = 367.5 +/- 80.1 no unit) | Homo sapiens | 4 | ALA3351891 | cell-based format | Scientific Literature | |
6. | ALA3372672 | F | Induction of superoxide generation in human HaCaT cells assessed as mean fluorescence intensity at 5 umol/L for 18 hrs chronic treatment in presence of dicoumarol NQO-1 inhibitor (Rvb = 407.6 +/- 68.7 no unit) | Homo sapiens | 4 | ALA3351891 | cell-based format | Scientific Literature | |
7. | ALA3372673 | F | Induction of superoxide generation in human HaCaT cells assessed as apoptotic cells at 5 umol/L for 18 hrs chronic treatment (Rvb = 3 +/- 1%) | Homo sapiens | 4 | ALA3351891 | cell-based format | Scientific Literature | |
8. | ALA3372674 | F | Induction of superoxide generation in human HaCaT cells assessed as apoptotic cells at 5 umol/L for 18 hrs chronic treatment in presence of dicoumarol NQO-1 inhibitor (Rvb = 4.3 +/- 2.6%) | Homo sapiens | 4 | ALA3351891 | cell-based format | Scientific Literature | |
9. | ALA3767225 | A | Cytotoxicity against human HaCaT cells assessed as LDH level at 2 uM incubated for 4 hrs | Homo sapiens | 28 | ALA3763096 | cell-based format | Scientific Literature | |
10. | ALA3767226 | F | Antihyperproliferative activity against human HaCaT cells after 48 hrs by phase contrast microscopic analysis | Homo sapiens | 35 | ALA3763096 | cell-based format | Scientific Literature | |
11. | ALA3767227 | B | Activity at human recombinant CPR assessed as superoxide generation at 100 umol/ml by spectrophotometric assay | Homo sapiens | 7 | ALA3763096 | single protein format | Scientific Literature | |
12. | ALA3767229 | F | Increase in superoxide generation in human HaCaT cells at 5 uM incubated for 18 hrs by DHE-based flow cytometric analysis | Homo sapiens | 6 | ALA3763096 | cell-based format | Scientific Literature | |
13. | ALA3767230 | F | Increase in superoxide generation in human HaCaT cells at 5 uM incubated for 18 hrs pretreated with 5 umol/L NQO1 inhibitor dicoumarol for 25 mins followed by compound addition by DHE-based flow cytometric analysis | Homo sapiens | 6 | ALA3763096 | cell-based format | Scientific Literature |