# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3375590 | B | Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP | Homo sapiens | 22 | ALA3352508 | single protein format | Scientific Literature | |
2. | ALA3375591 | F | Inhibition of LPS-induced TNFalpha release in human PBMC preincubated for 30 mins before LPS stimulation measured after 18 hrs by TR-FRET assay | Homo sapiens | 22 | ALA3352508 | cell-based format | Scientific Literature | |
3. | ALA3375592 | A | Drug metabolism in human liver microsomes assessed as extraction ratio measured up to 30 mins in presence of NADPH | Homo sapiens | 15 | ALA3352508 | assay format | Scientific Literature | |
4. | ALA3375593 | F | Antiinflammatory activity in topical allergic contact dermatitis mouse model assessed as inhibition of TNFalpha in tissue compound administered topically | Mus musculus | 1 | ALA3352508 | organism-based format | Scientific Literature | |
5. | ALA3375594 | F | Antiinflammatory activity in topical allergic contact dermatitis mouse model assessed as inhibition of TNFalpha in tissue at 0.001 mg administered topically | Mus musculus | 1 | ALA3352508 | organism-based format | Scientific Literature | |
6. | ALA3375595 | F | Antiinflammatory activity in topical allergic contact dermatitis mouse model assessed as inhibition of TNFalpha in tissue at 0.01 mg administered topically | Mus musculus | 1 | ALA3352508 | organism-based format | Scientific Literature | |
7. | ALA3375596 | F | Antiinflammatory activity in topical allergic contact dermatitis mouse model assessed as inhibition of TNFalpha in tissue at 0.1 mg administered topically | Mus musculus | 1 | ALA3352508 | organism-based format | Scientific Literature | |
8. | ALA3375598 | B | Inhibition of PDE1 (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3352508 | protein format | Scientific Literature | |
9. | ALA3375599 | B | Inhibition of PDE2 (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3352508 | single protein format | Scientific Literature | |
10. | ALA3375600 | B | Inhibition of PDE3 (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3352508 | protein format | Scientific Literature | |
11. | ALA3375601 | B | Inhibition of PDE9 (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3352508 | single protein format | Scientific Literature | |
12. | ALA3375602 | B | Inhibition of PDE5 (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3352508 | single protein format | Scientific Literature | |
13. | ALA3375603 | B | Inhibition of PDE7 (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3352508 | single protein format | Scientific Literature | |
14. | ALA3375604 | B | Inhibition of PDE8 (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3352508 | protein format | Scientific Literature | |
15. | ALA3375605 | B | Inhibition of PDE10 (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3352508 | single protein format | Scientific Literature | |
16. | ALA3375606 | B | Inhibition of PDE11 (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3352508 | single protein format | Scientific Literature | |
17. | ALA3375608 | P | Solubility of the compound in 0.067 M phosphate buffer at pH 7.4 | 2 | ALA3352508 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA3375609 | P | Solubility of the compound in 20 % hydroxypropyl-beta-cyclodextrin in water after 1 hr at room temperature | 3 | ALA3352508 | small-molecule physicochemical format | Scientific Literature | ||
19. | ALA3375610 | P | Solubility of the compound in medium chain triglyceride | 3 | ALA3352508 | small-molecule physicochemical format | Scientific Literature | ||
20. | ALA3375611 | P | Solubility of the compound in propylene glycol | 3 | ALA3352508 | small-molecule physicochemical format | Scientific Literature |