| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3366481 | B | Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | Homo sapiens | 18 | ALA3352762 | cell-based format | Scientific Literature | |
| 2. | ALA3366482 | B | Agonist activity at UT receptor in rat aorta assessed as contraction | Rattus norvegicus | 18 | ALA3352762 | tissue-based format | Scientific Literature | |
| 3. | ALA3366483 | B | Agonist activity at UT receptor in rat aorta assessed as contraction relative to urotensin-2 | Rattus norvegicus | 18 | ALA3352762 | tissue-based format | Scientific Literature | |
| 4. | ALA3366484 | B | Competitive antagonist activity at UT receptor in rat aorta assessed as effect on urotensin-2-induced contraction | Rattus norvegicus | 18 | ALA3352762 | tissue-based format | Scientific Literature | |
| 5. | ALA3366485 | F | Partial agonist activity at human recombinant UT receptor expressed in CHO-K1 cells assessed as stimulation of intracellular calcium mobilization by FLIPR assay | Homo sapiens | 3 | ALA3352762 | cell-based format | Scientific Literature | |
| 6. | ALA3366486 | F | Partial agonist activity at human recombinant UT receptor expressed in CHO-K1 cells assessed as stimulation of intracellular calcium mobilization at 1 uM by FLIPR assay relative to urotensin-2 | Homo sapiens | 3 | ALA3352762 | cell-based format | Scientific Literature | |
| 7. | ALA3366849 | F | Partial agonist activity at human recombinant UT receptor expressed in CHO-K1 cells assessed as stimulation of intracellular calcium mobilization at 10 uM by FLIPR assay relative to urotensin-2 | Homo sapiens | 3 | ALA3352762 | cell-based format | Scientific Literature | |
| 8. | ALA3366850 | A | Stability in 25% fetal calf serum assessed as parent compound remaining at 80 uM at 37 degC after 16 hrs by RP-HPLC-UV based detection assay | Bos taurus | 4 | ALA3352762 | assay format | Scientific Literature | |
| 9. | ALA3366851 | A | Stability in 25% fetal calf serum assessed as parent compound remaining at 80 uM at 37 degC after 36 hrs by RP-HPLC-UV based detection assay | Bos taurus | 4 | ALA3352762 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!