| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3364794 | B | Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry | Homo sapiens | 9 | ALA3351619 | cell-based format | Scientific Literature | |
| 2. | ALA3364795 | B | Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometry | Homo sapiens | 9 | ALA3351619 | cell-based format | Scientific Literature | |
| 3. | ALA3364796 | F | Agonist activity at human 5-HT7 expressed in HEK-293 cells assessed as increase in cAMP level after 45 mins by HTRF assay | Homo sapiens | 3 | ALA3351619 | cell-based format | Scientific Literature | |
| 4. | ALA3364797 | F | Agonist activity at human 5-HT7 expressed in HEK-293 cells assessed as increase in cAMP level after 45 mins by HTRF assay relative to control | Homo sapiens | 2 | ALA3351619 | cell-based format | Scientific Literature | |
| 5. | ALA3364798 | F | Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTRF assay | Homo sapiens | 3 | ALA3351619 | cell-based format | Scientific Literature | |
| 6. | ALA3364799 | B | Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as dissociation constant after 45 mins by HTRF assay | Homo sapiens | 3 | ALA3351619 | cell-based format | Scientific Literature | |
| 7. | ALA3364800 | B | Selectivity ratio of Ki for human 5-HT1A expressed in CHO-K1 cells to Ki for human 5-HT7 expressed in HEK-293 cells | Homo sapiens | 2 | ALA3351619 | cell-based format | Scientific Literature | |
| 8. | ALA3364801 | F | Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTRF assay relative to control | Homo sapiens | 2 | ALA3351619 | cell-based format | Scientific Literature | |
| 9. | ALA3364802 | F | Inhibition of 8-OH-DPAT-induced hypothermia in C57BL/6J mouse assessed as reduction in core body temperature at 1 mg/kg, ip administered 30 mins prior challenge as single dose | Mus musculus | 1 | ALA3351619 | organism-based format | Scientific Literature | |
| 10. | ALA3364803 | F | Effect on core body temperature in C57BL/6J mouse at 0.3 to 1 mg/kg, ip administered as single dose | Mus musculus | 1 | ALA3351619 | organism-based format | Scientific Literature | |
| 11. | ALA3364804 | F | Antidepressant activity in C57BL/6J mouse assessed as decrease in the immobility at 1 mg/kg, ip administered as single dose measured for last 4 mins of test by tail suspension method relative to vehicle-treated control | Mus musculus | 1 | ALA3351619 | organism-based format | Scientific Literature | |
| 12. | ALA3364805 | F | Antidepressant activity in C57BL/6J mouse assessed as decrease in the immobility at 10 mg/kg, ip administered as single dose measured for last 4 mins of test by tail suspension method relative to vehicle-treated control | Mus musculus | 1 | ALA3351619 | organism-based format | Scientific Literature | |
| 13. | ALA3364806 | F | Antidepressant activity in C57BL/6J mouse assessed as decrease in the immobility at 1 mg/kg, ip administered as single dose measured for last 4 mins of test by forced swim test relative to vehicle-treated control | Mus musculus | 1 | ALA3351619 | organism-based format | Scientific Literature | |
| 14. | ALA3364807 | B | Displacement of [3H]imipramine from 5-HT transporter (unknown origin) at 1 uM after 60 mins | Homo sapiens | 1 | ALA3351619 | single protein format | Scientific Literature | |
| 15. | ALA3365145 | B | Displacement of [125I]CYP from 5-HT1B (unknown origin) at 1 uM after 120 mins | Homo sapiens | 1 | ALA3351619 | single protein format | Scientific Literature | |
| 16. | ALA3365146 | B | Displacement of [3H]ketanserin from 5-HT2A (unknown origin) at 1 uM after 60 mins | Homo sapiens | 1 | ALA3351619 | single protein format | Scientific Literature | |
| 17. | ALA3365147 | B | Displacement of [3H]mesulergine from 5-HT2C (unknown origin) at 1 uM after 120 mins | Homo sapiens | 1 | ALA3351619 | single protein format | Scientific Literature | |
| 18. | ALA3365148 | B | Displacement of [125I]-2-iodomelatonin from MT1 (unknown origin) at 1 uM after 60 mins | Homo sapiens | 1 | ALA3351619 | protein format | Scientific Literature | |
| 19. | ALA3365149 | B | Displacement of [125I]sauvagine from CRF1 (unknown origin) at 1 uM after 120 mins | Homo sapiens | 1 | ALA3351619 | single protein format | Scientific Literature | |
| 20. | ALA4343396 | B | Antagonist activity at 5-HT7 receptor (unknown origin) | Homo sapiens | 21 | ALA4342419 | single protein format | Scientific Literature |
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