| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3368714 | B | Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's method | Rattus norvegicus | 19 | ALA3351918 | assay format | Scientific Literature | |
| 2. | ALA3368715 | B | Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's method | Rattus norvegicus | 19 | ALA3351918 | cell-free format | Scientific Literature | |
| 3. | ALA3368716 | B | Potency index, ratio of IC50 for rivastigmine to IC50 for test compound against AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's method | Rattus norvegicus | 1 | ALA3351918 | assay format | Scientific Literature | |
| 4. | ALA3368718 | B | Inhibition of Amyloid beta (1 to 40) (unknown origin) assessed as self-mediated fibril formation at 50 uM incubated for 48 hrs by transmission electron microscopy | Homo sapiens | 5 | ALA3351918 | single protein format | Scientific Literature | |
| 5. | ALA3368937 | A | Prodrug activation in rat cortex homogenates assessed as AChE-mediated 2-methoxy-4-(piperidin-1-ylmethyl)phenol formation at 1 mmol after 24 hrs by HPLC-MS method | Rattus norvegicus | 1 | ALA3351918 | assay format | Scientific Literature | |
| 6. | ALA3368939 | A | Retention time in rat cortex homogenates at 1 mmol after 24 hrs by HPLC-MS method | Rattus norvegicus | 2 | ALA3351918 | assay format | Scientific Literature | |
| 7. | ALA5226500 | B | Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's method | Rattus norvegicus | 1 | ALA5226281 | assay format | Scientific Literature |
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