| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3367584 | B | Inhibition of 6-His-tagged Mycobacterium smegmatis GyrB expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 100 mins in presence of ATP by malachite green dye based ATP assay | Mycolicibacterium smegmatis | 32 | ALA3352198 | cell-based format | Scientific Literature | |
| 2. | ALA3367585 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase supercoiling activity using relaxed pBR322 substrate incubated for 30 mins by ethidium bromide staining method | Mycobacterium tuberculosis | 32 | ALA3352198 | assay format | Scientific Literature | |
| 3. | ALA3367586 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv after 7 days by microplate alamar blue assay method | Mycobacterium tuberculosis | 32 | ALA3352198 | organism-based format | Scientific Literature | |
| 4. | ALA3367587 | A | Cytotoxicity against mouse RAW264.7 cells assessed as inhibition of cell viability at 100 uM after 48 hrs by MTT assay | Mus musculus | 31 | ALA3352198 | cell-based format | Scientific Literature | |
| 5. | ALA3367588 | B | Inhibition of Staphylococcus aureus GyrB at 50 uM | Staphylococcus aureus | 1 | ALA3352198 | single protein format | Scientific Literature | |
| 6. | ALA3367589 | B | Inhibition of Escherichia coli GyrB at 50 uM | Escherichia coli | 1 | ALA3352198 | single protein format | Scientific Literature | |
| 7. | ALA3367590 | B | Binding affinity to Mycobacterium smegmatis GyrB expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as change in melting temperature by SYPRO orange dye staining based differential scanning fluorimetry | Mycolicibacterium smegmatis | 1 | ALA3352198 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!