# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3374323 | Binding | Inhibition of androgen receptor transcriptional activity in human LNCaP cells after 3 days by eGFP assay | Homo sapiens | 45 | ALA3352043 | cell-based format | Scientific Literature | |
2. | ALA3374324 | Binding | Inhibition of androgen receptor in human LNCaP cells assessed as inhibition of prostate-specific antigen secretion into media after 3 days | Homo sapiens | 36 | ALA3352043 | cell-based format | Scientific Literature | |
3. | ALA3374325 | Functional | Growth inhibition of AR-dependent human LNCAP cells after 3 days by MTS assay | Homo sapiens | 1 | ALA3352043 | cell-based format | Scientific Literature | |
4. | ALA3374326 | Functional | Growth inhibition of enzalutamide-resistant human MR49F cells after 3 days by MTS assay | Homo sapiens | 1 | ALA3352043 | cell-based format | Scientific Literature | |
5. | ALA3374327 | ADME | Growth inhibition of AR-negative human PC3 cells after 3 days by MTS assay | Homo sapiens | 2 | ALA3352043 | cell-based format | Scientific Literature | |
6. | ALA3374328 | Binding | Inhibition of human androgen receptor Q592D mutant expressed in human PC3 cells assessed as inhibition of transcription activity after 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA3352043 | cell-based format | Scientific Literature | |
7. | ALA3374329 | Binding | Inhibition of human androgen receptor Y594D mutant expressed in human PC3 cells assessed as inhibition of transcription activity after 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA3352043 | cell-based format | Scientific Literature | |
8. | ALA3374330 | Binding | Displacement of androgen from androgen receptor (unknown origin) by Polarscreen competitor green assay | Homo sapiens | 2 | ALA3352043 | single protein format | Scientific Literature | |
9. | ALA3374331 | Binding | Binding affinity to biotinylated androgen receptor LBD (unknown origin) expressed in Escherichia coli BL21 by biolayer interferometry assay | Homo sapiens | 2 | ALA3352043 | assay format | Scientific Literature | |
10. | ALA3374332 | Binding | Inhibition of androgen receptor V7 (unknown origin) expressed in human PC3 cells assessed as inhibition of transcription activity after 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA3352043 | cell-based format | Scientific Literature | |
11. | ALA3374333 | Binding | Inhibition of progesterone receptor (unknown origin) transcriptional activity at 10 mM | Homo sapiens | 2 | ALA3352043 | single protein format | Scientific Literature | |
12. | ALA3374334 | Binding | Inhibition of glucocorticoid receptor (unknown origin) transcriptional activity at 10 mM | Homo sapiens | 2 | ALA3352043 | single protein format | Scientific Literature | |
13. | ALA3374335 | Binding | Inhibition of ERalpha (unknown origin) transcriptional activity at 10 mM | Homo sapiens | 2 | ALA3352043 | single protein format | Scientific Literature | |
14. | ALA3374337 | Physicochemical | Stability of the compound in RPMI plus 5% charcoal stripped serum media after 1 hr by MS analysis | 3 | ALA3352043 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA5140935 | Functional | Antiproliferative activity against human LNCaP cells | Homo sapiens | 9 | ALA5137058 | cell-based format | Scientific Literature | |
16. | ALA5140966 | Binding | Antagonist activity at Androgen receptor in human LNCaP cells assessed as inhibition of PSA expression | Homo sapiens | 5 | ALA5137058 | cell-based format | Scientific Literature | |
17. | ALA5140997 | Binding | Antagonist activity at Androgen receptor in human LNCaP cells assessed as inhibition of DNA binding domain of AR measured by enhanced green fluorescent protein transcriptional (eGFPT) assay | Homo sapiens | 3 | ALA5137058 | cell-based format | Scientific Literature | |
18. | ALA5140998 | Functional | Antiproliferative activity against human MR49F cells | Homo sapiens | 1 | ALA5137058 | cell-based format | Scientific Literature |