# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3370046 | F | Antiplasmodial activity against schizont blood stage Plasmodium falciparum | Plasmodium falciparum | 14 | ALA3352748 | organism-based format | Scientific Literature | |
2. | ALA3370047 | F | Antiplasmodial activity against blood stage schizont Plasmodium yoelii | Plasmodium yoelii | 14 | ALA3352748 | organism-based format | Scientific Literature | |
3. | ALA3370048 | F | Antiplasmodial activity against schizont liver stage Plasmodium cynomolgi | Plasmodium cynomolgi | 6 | ALA3352748 | organism-based format | Scientific Literature | |
4. | ALA3370049 | F | Antiplasmodial activity against hypnozoite liver stage Plasmodium cynomolgi | Plasmodium cynomolgi | 8 | ALA3352748 | organism-based format | Scientific Literature | |
5. | ALA3370050 | P | Solubility of the compound at pH 6.8 by HT-equilibrium solubility assay | 5 | ALA3352748 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA3370051 | A | Hepatic extraction ratio in mouse liver microsomes by LC/MS analysis | Mus musculus | 4 | ALA3352748 | assay format | Scientific Literature | |
7. | ALA3370052 | A | Half life in mouse liver microsomes by LC/MS analysis | Mus musculus | 4 | ALA3352748 | assay format | Scientific Literature | |
8. | ALA3370053 | A | Cmax in mouse at 20 mg/kg, po | Mus musculus | 4 | ALA3352748 | organism-based format | Scientific Literature | |
9. | ALA3370054 | A | Tmax in mouse at 20 mg/kg, po | Mus musculus | 4 | ALA3352748 | organism-based format | Scientific Literature | |
10. | ALA3370055 | A | AUC in mouse at 20 mg/kg, po | Mus musculus | 4 | ALA3352748 | organism-based format | Scientific Literature | |
11. | ALA3370056 | A | Half life in mouse at 20 mg/kg, po | Mus musculus | 4 | ALA3352748 | organism-based format | Scientific Literature | |
12. | ALA3370057 | A | Oral bioavailability in mouse at 20 mg/kg | Mus musculus | 4 | ALA3352748 | organism-based format | Scientific Literature | |
13. | ALA3370058 | A | Volume of distribution at steady state in mouse at 5 mg/kg, iv | Mus musculus | 4 | ALA3352748 | organism-based format | Scientific Literature | |
14. | ALA3370059 | A | Clearance in mouse at 5 mg/kg, iv | Mus musculus | 4 | ALA3352748 | organism-based format | Scientific Literature | |
15. | ALA3370060 | A | Half life in mouse at 5 mg/kg, iv | Mus musculus | 4 | ALA3352748 | organism-based format | Scientific Literature | |
16. | ALA3370061 | F | Antimalarial activity against Plasmodium berghei infected in mouse assessed as animal protection at 30 mg/kg, po by causal prophylactic activity assay relative to untreated control | Plasmodium berghei | 2 | ALA3352748 | organism-based format | Scientific Literature |