# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3367077 | B | Displacement of [33P]2MeS-ADP from P2Y12 receptor (unknown origin) transfected in CHO cells after 30 mins by scintillation counting analysis | Homo sapiens | 89 | ALA3352233 | cell-based format | Scientific Literature | |
2. | ALA3367079 | B | Antagonist activity at P2Y12 receptor in Sprague-Dawley rat platelet rich plasma assessed as inhibition of ADP-induced aggregation | Rattus norvegicus | 89 | ALA3352233 | cell-free format | Scientific Literature | |
3. | ALA3367080 | A | Permeability across human Caco2 cells | Homo sapiens | 28 | ALA3352233 | cell-based format | Scientific Literature | |
4. | ALA3361768 | A | Metabolic stability in human liver microsomes assessed as compound metabolism after 20 mins incubation in presence of 1 mM NADPH | Homo sapiens | 31 | ALA3352233 | assay format | Scientific Literature | |
5. | ALA3361769 | A | Metabolic stability in rat liver microsomes assessed as compound metabolism after 20 mins incubation in presence of 1 mM NADPH | Rattus norvegicus | 30 | ALA3352233 | assay format | Scientific Literature | |
6. | ALA3361773 | A | Metabolic stability in mouse liver microsomes assessed as compound metabolism after 20 mins incubation in presence of 1 mM NADPH | Mus musculus | 4 | ALA3352233 | assay format | Scientific Literature | |
7. | ALA3361774 | A | Intrinsic metabolic clearance in human hepatocytes measured per 10'6 cells after 24 hrs | Homo sapiens | 4 | ALA3352233 | cell-based format | Scientific Literature | |
8. | ALA3361775 | A | Intrinsic metabolic clearance in human hepatocytes measured assessed as CYP3A4 contribution per 10'6 cells after 24 hrs | Homo sapiens | 4 | ALA3352233 | cell-based format | Scientific Literature |