# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3361506 | B | Inhibition of constitutively activated GST-tagged human MEK1 S218D/S22D (MEK1DD) mutant assessed blocking of increase in bovine MBP kinase activity of recombinant His6-tagged ERK2 using [gamma32P]ATP by liquid scintillation counting method | Homo sapiens | 15 | assay format | Scientific Literature | ||
2. | ALA3361507 | B | Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 mins by immunoblotting method | Rattus norvegicus | 15 | organism-based format | Scientific Literature | ||
3. | ALA3361509 | F | Antiproliferative activity against human HT-29 cells after 5 days by WST1 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA3361510 | F | Antiproliferative activity against human A375 cells after 5 days by WST1 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA3361511 | F | Antiproliferative activity against human A549 cells after 5 days by WST1 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA3361512 | F | Antiproliferative activity against human HCT116 cells after 5 days by WST1 assay | Homo sapiens | 2 | cell-based format | Scientific Literature |