# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3365532 | B | Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay | Homo sapiens | 33 | ALA3352666 | cell-based format | Scientific Literature | |
2. | ALA3365533 | B | Agonist activity at human TLR2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay | Homo sapiens | 33 | ALA3352666 | cell-based format | Scientific Literature | |
3. | ALA3365534 | B | Agonist activity at human TLR3 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay | Homo sapiens | 33 | ALA3352666 | cell-based format | Scientific Literature | |
4. | ALA3365535 | B | Agonist activity at human TLR4 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay | Homo sapiens | 33 | ALA3352666 | cell-based format | Scientific Literature | |
5. | ALA3365536 | B | Agonist activity at human TLR5 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay | Homo sapiens | 33 | ALA3352666 | cell-based format | Scientific Literature | |
6. | ALA3365537 | B | Agonist activity at human TLR7 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay | Homo sapiens | 33 | ALA3352666 | cell-based format | Scientific Literature | |
7. | ALA3365538 | B | Agonist activity at human TLR9 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay | Homo sapiens | 33 | ALA3352666 | cell-based format | Scientific Literature | |
8. | ALA3365539 | B | Agonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay | Homo sapiens | 33 | ALA3352666 | cell-based format | Scientific Literature | |
9. | ALA3365540 | B | Agonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay | Homo sapiens | 33 | ALA3352666 | cell-based format | Scientific Literature | |
10. | ALA3361800 | B | Induction of TLR8-mediated IL-12p40 in human PBMC after 12 hrs by immunoassay | Homo sapiens | 1 | ALA3352666 | single protein format | Scientific Literature | |
11. | ALA3361801 | B | Induction of TLR8-mediated IFN-gamma in human PBMC after 12 hrs by immunoassay | Homo sapiens | 1 | ALA3352666 | single protein format | Scientific Literature | |
12. | ALA3361802 | F | Upregulation of CD69 expression in human NK cells at 0.1 to 10 ug/ml measured after overnight incubation by flow cytometry | Homo sapiens | 1 | ALA3352666 | cell-based format | Scientific Literature | |
13. | ALA4429195 | B | Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 15 | ALA4428062 | cell-based format | Scientific Literature | |
14. | ALA4429196 | B | Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
15. | ALA4429197 | B | Agonist activity at human TLR3 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
16. | ALA4429198 | B | Agonist activity at human TLR4 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
17. | ALA4429199 | B | Agonist activity at human TLR5 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
18. | ALA4429200 | B | Agonist activity at human TLR7 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
19. | ALA4429201 | B | Agonist activity at human TLR9 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
20. | ALA4429202 | B | Agonist activity at TLR8 in human PBMC assessed as increase in TNF-alpha production after 16 hrs by immunoassay | Homo sapiens | 5 | ALA4428062 | single protein format | Scientific Literature |