# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3361514 | P | Solubility of the compound in 0.1 M sodium phosphate buffer at pH 7.4 | 32 | ALA3351722 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA3361515 | B | Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assay | Homo sapiens | 32 | ALA3351722 | single protein format | Scientific Literature | |
3. | ALA3361516 | B | Inhibition of human recombinant soluble epoxide hydrolase assessed as half-life of enzyme-inhibitor complex by FRET-based ACPU displacement assay | Homo sapiens | 20 | ALA3351722 | single protein format | Scientific Literature | |
4. | ALA3370766 | A | AUC in Swiss Webster mouse at 0.3 mg/kg, po administered as cassette dosing | Mus musculus | 20 | ALA3351722 | organism-based format | Scientific Literature | |
5. | ALA3370767 | A | Cmax in Swiss Webster mouse at 0.3 mg/kg, po administered as cassette dosing | Mus musculus | 20 | ALA3351722 | organism-based format | Scientific Literature | |
6. | ALA3370768 | A | Half life in Swiss Webster mouse at 0.3 mg/kg, po administered as cassette dosing | Mus musculus | 20 | ALA3351722 | organism-based format | Scientific Literature | |
7. | ALA3370769 | A | Tmax in Swiss Webster mouse at 0.3 mg/kg, po administered as cassette dosing | Mus musculus | 20 | ALA3351722 | organism-based format | Scientific Literature | |
8. | ALA3371004 | B | Inhibition of human ERG expressed in HEK-293 cells at 50 uM by whole-cell patch-clamp technique | Homo sapiens | 7 | ALA3351722 | cell-based format | Scientific Literature | |
9. | ALA3371005 | A | Protein binding in human plasma at 1 uM | Homo sapiens | 7 | ALA3351722 | cell-free format | Scientific Literature | |
10. | ALA3371006 | A | Inhibition of human CYP2J2 assessed as remaining activity at 10 uM | Homo sapiens | 7 | ALA3351722 | single protein format | Scientific Literature | |
11. | ALA3371007 | A | Inhibition of human CYP2C assessed as remaining activity at 10 uM | Homo sapiens | 7 | ALA3351722 | assay format | Scientific Literature | |
12. | ALA3371009 | B | Inhibition of rat soluble epoxide hydrolase using [3H]-t-DPPO as a substrate by radiometric assay | Rattus norvegicus | 6 | ALA3351722 | single protein format | Scientific Literature | |
13. | ALA3371010 | B | Inhibition of rat soluble epoxide hydrolase assessed as half-life of enzyme-inhibitor complex by FRET-based ACPU displacement assay | Rattus norvegicus | 6 | ALA3351722 | single protein format | Scientific Literature | |
14. | ALA3371011 | A | AUC in Sprague-Dawley rat at 0.3 mg/kg, po administered as cassette dosing | Rattus norvegicus | 4 | ALA3351722 | organism-based format | Scientific Literature | |
15. | ALA3371012 | A | Cmax in Sprague-Dawley rat at 0.3 mg/kg, po administered as cassette dosing | Rattus norvegicus | 4 | ALA3351722 | organism-based format | Scientific Literature | |
16. | ALA3371013 | A | Half life in Sprague-Dawley rat at 0.3 mg/kg, po administered as cassette dosing | Rattus norvegicus | 4 | ALA3351722 | organism-based format | Scientific Literature | |
17. | ALA3371014 | A | Tmax in Sprague-Dawley rat at 0.3 mg/kg, po administered as cassette dosing | Rattus norvegicus | 4 | ALA3351722 | organism-based format | Scientific Literature | |
18. | ALA3371019 | P | Lipophilicity, log P of the compound by shake-flask method | 32 | ALA3351722 | small-molecule physicochemical format | Scientific Literature | ||
19. | ALA3887156 | B | FA: fluoresence competitive assay. | 15 | ALA3886192 | single protein format | BindingDB Database | ||
20. | ALA3887157 | B | t-DPPO: Trans-diphenylpropene oxide is used in a radiometric competitive assay. | 15 | ALA3886192 | single protein format | BindingDB Database |