# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3361514 | P | Solubility of the compound in 0.1 M sodium phosphate buffer at pH 7.4 | 32 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA3361515 | B | Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
3. | ALA3361516 | B | Inhibition of human recombinant soluble epoxide hydrolase assessed as half-life of enzyme-inhibitor complex by FRET-based ACPU displacement assay | Homo sapiens | 20 | single protein format | Scientific Literature | ||
4. | ALA3370766 | A | AUC in Swiss Webster mouse at 0.3 mg/kg, po administered as cassette dosing | Mus musculus | 20 | organism-based format | Scientific Literature | ||
5. | ALA3370767 | A | Cmax in Swiss Webster mouse at 0.3 mg/kg, po administered as cassette dosing | Mus musculus | 20 | organism-based format | Scientific Literature | ||
6. | ALA3370768 | A | Half life in Swiss Webster mouse at 0.3 mg/kg, po administered as cassette dosing | Mus musculus | 20 | organism-based format | Scientific Literature | ||
7. | ALA3370769 | A | Tmax in Swiss Webster mouse at 0.3 mg/kg, po administered as cassette dosing | Mus musculus | 20 | organism-based format | Scientific Literature | ||
8. | ALA3371004 | B | Inhibition of human ERG expressed in HEK-293 cells at 50 uM by whole-cell patch-clamp technique | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
9. | ALA3371005 | A | Protein binding in human plasma at 1 uM | Homo sapiens | 7 | cell-free format | Scientific Literature | ||
10. | ALA3371006 | A | Inhibition of human CYP2J2 assessed as remaining activity at 10 uM | Homo sapiens | 7 | single protein format | Scientific Literature | ||
11. | ALA3371007 | A | Inhibition of human CYP2C assessed as remaining activity at 10 uM | Homo sapiens | 7 | assay format | Scientific Literature | ||
12. | ALA3371008 | B | Selectivity ratio of Ki for human ERG expressed in HEK-293 cells to Ki for human recombinant soluble epoxide hydrolase | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA3371009 | B | Inhibition of rat soluble epoxide hydrolase using [3H]-t-DPPO as a substrate by radiometric assay | Rattus norvegicus | 6 | single protein format | Scientific Literature | ||
14. | ALA3371010 | B | Inhibition of rat soluble epoxide hydrolase assessed as half-life of enzyme-inhibitor complex by FRET-based ACPU displacement assay | Rattus norvegicus | 6 | single protein format | Scientific Literature | ||
15. | ALA3371011 | A | AUC in Sprague-Dawley rat at 0.3 mg/kg, po administered as cassette dosing | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
16. | ALA3371012 | A | Cmax in Sprague-Dawley rat at 0.3 mg/kg, po administered as cassette dosing | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
17. | ALA3371013 | A | Half life in Sprague-Dawley rat at 0.3 mg/kg, po administered as cassette dosing | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
18. | ALA3371014 | A | Tmax in Sprague-Dawley rat at 0.3 mg/kg, po administered as cassette dosing | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
19. | ALA3371019 | P | Lipophilicity, log P of the compound by shake-flask method | 32 | small-molecule physicochemical format | Scientific Literature |