#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3366730	Binding	Inhibition of HDAC in human HCT116 cells assessed as increase in histone H3 (Lys9/14) hyperacetylation at 320 pM to 10 uM after 8 to 24 hrs by immunoblotting method	Homo sapiens	1	ALA3352121	cell-based format	Scientific Literature
2.	ALA3366733	ADME	Drug metabolism in human HCT116 cells protein lysate solution assessed as largazole thiol formation at 25 ug/mL after 4 hrs by HPLC-MS method	Homo sapiens	1	ALA3352121	cell-based format	Scientific Literature
3.	ALA3366737	ADME	Drug metabolism in mouse serum assessed as largazole thiol formation after 0.25 to 1440 mins by HPLC-MS method	Mus musculus	3	ALA3352121	cell-free format	Scientific Literature
4.	ALA3365360	Functional	In vivo inhibition of HDAC in tumor of human HCT116 cells xenografted nu/nu mouse assessed as increase in histone hyperacetylation at 10 mg/kg, ip after 24 hrs by immunoblotting method	Homo sapiens	1	ALA3352121	organism-based format	Scientific Literature
5.	ALA3365363	Functional	In vivo inhibition of HDAC in tumor of human HCT116 cells xenografted nu/nu mouse assessed as increase in histone hyperacetylation at 50 mg/kg, ip after 24 hrs by immunoblotting method	Homo sapiens	1	ALA3352121	organism-based format	Scientific Literature
6.	ALA3365694	Functional	In vivo inhibition of HDAC in tumor of human HCT116 cells xenografted nu/nu mouse assessed as increase in histone hyperacetylation at 50 mg/kg, po after 4 to 12 hrs by immunoblotting method	Homo sapiens	3	ALA3352121	organism-based format	Scientific Literature
7.	ALA3365695	ADME	Drug metabolism in tumor of human HCT116 cells xenografted nu/nu mouse assessed largazole thiol formation at 10 mg/kg, po by HPLC-MS method	Homo sapiens	3	ALA3352121	organism-based format	Scientific Literature