# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3369251 | T | Toxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 0.01 to 1 uM incubated for 24 hrs by MTT assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
2. | ALA3369253 | F | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of iNOS protein expression at 0.01 to 1 uM pre-incubated for 30 mins before LPS stimulation for 24 hrs by Western blotting method | Mus musculus | 4 | cell-based format | Scientific Literature | ||
3. | ALA3369254 | F | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of COX2 protein expression at 0.01 to 1 uM pre-incubated for 30 mins before LPS stimulation for 24 hrs by Western blotting method | Mus musculus | 4 | cell-based format | Scientific Literature | ||
4. | ALA3369255 | B | Inhibition of p65 phosphorylation in LPS-stimulated mouse RAW264.7 cells at 0.01 to 1 uM pre-incubated for 30 mins before LPS stimulation for 24 hrs by Western blotting method | Mus musculus | 4 | cell-based format | Scientific Literature | ||
5. | ALA3369256 | B | Inhibition of HDAC in LPS-stimulated mouse RAW264.7 cells assessed as increase in histone H3 acetylation at > 0.1 uM pre-incubated for 30 mins before LPS stimulation for 24 hrs by Western blotting method | Mus musculus | 4 | cell-based format | Scientific Literature | ||
6. | ALA3369257 | F | Anti-inflammatory activity in Wistar rat model of carrageenan-induced edema assessed as reduction in right hind paw thickness at 20 mg/kg, po dosed 1 hour before carrageenan injection measured 3 hrs post carrageenan challenge by digital plethysmometry | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
7. | ALA3369491 | B | Inhibition of HDAC in human HeLa cells nuclear extracts incubated for 30 mins by fluorescent assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
8. | ALA3369492 | F | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of nitric oxide production pre-incubated for 1 hr before LPS stimulation for 24 hrs by Griess reagent based assay | Mus musculus | 14 | cell-based format | Scientific Literature | ||
9. | ALA3369493 | F | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of TNFalpha production pre-incubated for 1 hr before LPS stimulation for 24 hrs by ELISA method | Mus musculus | 14 | cell-based format | Scientific Literature | ||
10. | ALA3369494 | F | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of IL6 production pre-incubated for 1 hr before LPS stimulation for 24 hrs by ELISA method | Mus musculus | 14 | cell-based format | Scientific Literature | ||
11. | ALA3369495 | F | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of PGE2 production pre-incubated for 1 hr before LPS stimulation for 24 hrs by enzyme immunoassay method | Mus musculus | 14 | cell-based format | Scientific Literature | ||
12. | ALA3369496 | P | Retention time of the compound by HPLC method | 12 | small-molecule physicochemical format | Scientific Literature | |||
13. | ALA5230941 | B | Inhibition of HDAC3 (unknown origin) | Homo sapiens | 5 | single protein format | Scientific Literature | ||
14. | ALA5230966 | B | Inhibition of HDAC1 (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
15. | ALA5230967 | B | Inhibition of HDAC2 (unknown origin) | Homo sapiens | 11 | single protein format | Scientific Literature | ||
16. | ALA5230968 | B | Inhibition of HDAC6 (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
17. | ALA5231011 | F | Cytotoxicity against human A549 cells assessed as inhibition of cell growth by SRB assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
18. | ALA5231012 | F | Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by SRB assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
19. | ALA5231020 | F | Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by SRB assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA5231021 | F | Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by SRB assay | Homo sapiens | 4 | cell-based format | Scientific Literature |