# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3369251 | Toxicity | Toxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 0.01 to 1 uM incubated for 24 hrs by MTT assay | Mus musculus | 4 | ALA3351972 | cell-based format | Scientific Literature | |
2. | ALA3369253 | Functional | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of iNOS protein expression at 0.01 to 1 uM pre-incubated for 30 mins before LPS stimulation for 24 hrs by Western blotting method | Mus musculus | 4 | ALA3351972 | cell-based format | Scientific Literature | |
3. | ALA3369254 | Functional | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of COX2 protein expression at 0.01 to 1 uM pre-incubated for 30 mins before LPS stimulation for 24 hrs by Western blotting method | Mus musculus | 4 | ALA3351972 | cell-based format | Scientific Literature | |
4. | ALA3369255 | Binding | Inhibition of p65 phosphorylation in LPS-stimulated mouse RAW264.7 cells at 0.01 to 1 uM pre-incubated for 30 mins before LPS stimulation for 24 hrs by Western blotting method | Mus musculus | 4 | ALA3351972 | cell-based format | Scientific Literature | |
5. | ALA3369256 | Binding | Inhibition of HDAC in LPS-stimulated mouse RAW264.7 cells assessed as increase in histone H3 acetylation at > 0.1 uM pre-incubated for 30 mins before LPS stimulation for 24 hrs by Western blotting method | Mus musculus | 4 | ALA3351972 | cell-based format | Scientific Literature | |
6. | ALA3369257 | Functional | Anti-inflammatory activity in Wistar rat model of carrageenan-induced edema assessed as reduction in right hind paw thickness at 20 mg/kg, po dosed 1 hour before carrageenan injection measured 3 hrs post carrageenan challenge by digital plethysmometry | Rattus norvegicus | 5 | ALA3351972 | organism-based format | Scientific Literature | |
7. | ALA3369491 | Binding | Inhibition of HDAC in human HeLa cells nuclear extracts incubated for 30 mins by fluorescent assay | Homo sapiens | 14 | ALA3351972 | cell-based format | Scientific Literature | |
8. | ALA3369492 | Functional | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of nitric oxide production pre-incubated for 1 hr before LPS stimulation for 24 hrs by Griess reagent based assay | Mus musculus | 14 | ALA3351972 | cell-based format | Scientific Literature | |
9. | ALA3369493 | Functional | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of TNFalpha production pre-incubated for 1 hr before LPS stimulation for 24 hrs by ELISA method | Mus musculus | 14 | ALA3351972 | cell-based format | Scientific Literature | |
10. | ALA3369494 | Functional | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of IL6 production pre-incubated for 1 hr before LPS stimulation for 24 hrs by ELISA method | Mus musculus | 14 | ALA3351972 | cell-based format | Scientific Literature | |
11. | ALA3369495 | Functional | Anti-inflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as suppression of PGE2 production pre-incubated for 1 hr before LPS stimulation for 24 hrs by enzyme immunoassay method | Mus musculus | 14 | ALA3351972 | cell-based format | Scientific Literature | |
12. | ALA3369496 | Physicochemical | Retention time of the compound by HPLC method | 12 | ALA3351972 | small-molecule physicochemical format | Scientific Literature |