# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3370155 | B | Inhibition of human recombinant DPP4 expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assay | Homo sapiens | 27 | ALA3351537 | assay format | Scientific Literature | |
2. | ALA3370156 | B | Inhibition of DPP7 (unknown origin) expressed in baculovirus expression system using Nle-Pro-AMC as substrate by continuous fluorometric assay | Homo sapiens | 27 | ALA3351537 | assay format | Scientific Literature | |
3. | ALA3370157 | B | Inhibition of DPP8 (unknown origin) expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assay | Homo sapiens | 27 | ALA3351537 | assay format | Scientific Literature | |
4. | ALA3370158 | B | Inhibition of DPP9 (unknown origin) expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assay | Homo sapiens | 27 | ALA3351537 | assay format | Scientific Literature | |
5. | ALA3370159 | B | Inhibition of FAP (unknown origin) expressed in baculovirus expression system using Nle-Pro-AMC as substrate by continuous fluorometric assay | Homo sapiens | 27 | ALA3351537 | assay format | Scientific Literature | |
6. | ALA3370160 | B | Selectivity ratio of IC50 for DPP8 (unknown origin) expressed in baculovirus expression system to IC50 for human recombinant DPP4 expressed in baculovirus expression system | Homo sapiens | 17 | ALA3351537 | assay format | Scientific Literature | |
7. | ALA3370161 | B | Selectivity ratio of IC50 for DPP9 (unknown origin) expressed in baculovirus expression system to IC50 for human recombinant DPP4 expressed in baculovirus expression system | Homo sapiens | 18 | ALA3351537 | assay format | Scientific Literature | |
8. | ALA3370162 | F | Reduction in glucose excursion in ICR mouse assessed as glucose AUC (0 to 120 mins) at 5 mg/kg administered as single dose by oral glucose tolerance test (Rvb = 1175.5 +/- 216.4 mmol/L/min) | Mus musculus | 2 | ALA3351537 | organism-based format | Scientific Literature | |
9. | ALA3370163 | F | Reduction in glucose excursion in ICR mouse assessed as glucose AUC (0 to 120 mins) at 15 mg/kg administered as single dose by oral glucose tolerance test (Rvb = 1175.5 +/- 216.4 mmol/L/min) | Mus musculus | 3 | ALA3351537 | organism-based format | Scientific Literature | |
10. | ALA3370164 | F | Reduction in glucose excursion in ICR mouse compound administered as single dose measured at 15 mins post dose by oral glucose tolerance test | Mus musculus | 2 | ALA3351537 | organism-based format | Scientific Literature | |
11. | ALA3370172 | A | Tmax in Sprague-Dawley rat at 50 mg/kg, po | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature | |
12. | ALA3370173 | A | Cmax in Sprague-Dawley rat at 50 mg/kg, po | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature | |
13. | ALA3370174 | A | AUC (0 to t) in Sprague-Dawley rat at 50 mg/kg, po | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature | |
14. | ALA3370175 | A | AUC (0 to infinity) in Sprague-Dawley rat at 50 mg/kg, po | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature | |
15. | ALA3370176 | A | Mean residence time in Sprague-Dawley rat at 50 mg/kg, po | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature | |
16. | ALA3370177 | A | Half life in Sprague-Dawley rat at 50 mg/kg, po | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature | |
17. | ALA3370179 | A | Oral bioavailability in Sprague-Dawley rat at 50 mg/kg | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature | |
18. | ALA3370415 | A | Tmax in Sprague-Dawley rat at 20 mg/kg, iv | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature | |
19. | ALA3370416 | A | Cmax in Sprague-Dawley rat at 20 mg/kg, iv | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature | |
20. | ALA3370417 | A | AUC (0 to t) in Sprague-Dawley rat at 20 mg/kg, iv | Rattus norvegicus | 1 | ALA3351537 | organism-based format | Scientific Literature |