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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3370155 Binding Inhibition of human recombinant DPP4 expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assay Homo sapiens 27 ALA3351537 assay format Scientific Literature 2. ALA3370156 Binding Inhibition of DPP7 (unknown origin) expressed in baculovirus expression system using Nle-Pro-AMC as substrate by continuous fluorometric assay Homo sapiens 27 ALA3351537 assay format Scientific Literature 3. ALA3370157 Binding Inhibition of DPP8 (unknown origin) expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assay Homo sapiens 27 ALA3351537 assay format Scientific Literature 4. ALA3370158 Binding Inhibition of DPP9 (unknown origin) expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assay Homo sapiens 27 ALA3351537 assay format Scientific Literature 5. ALA3370159 Binding Inhibition of FAP (unknown origin) expressed in baculovirus expression system using Nle-Pro-AMC as substrate by continuous fluorometric assay Homo sapiens 27 ALA3351537 assay format Scientific Literature 6. ALA3370160 Binding Selectivity ratio of IC50 for DPP8 (unknown origin) expressed in baculovirus expression system to IC50 for human recombinant DPP4 expressed in baculovirus expression system Homo sapiens 17 ALA3351537 assay format Scientific Literature 7. ALA3370161 Binding Selectivity ratio of IC50 for DPP9 (unknown origin) expressed in baculovirus expression system to IC50 for human recombinant DPP4 expressed in baculovirus expression system Homo sapiens 18 ALA3351537 assay format Scientific Literature 8. ALA3370162 Functional Reduction in glucose excursion in ICR mouse assessed as glucose AUC (0 to 120 mins) at 5 mg/kg administered as single dose by oral glucose tolerance test (Rvb = 1175.5 +/- 216.4 mmol/L/min) Mus musculus 2 ALA3351537 organism-based format Scientific Literature 9. ALA3370163 Functional Reduction in glucose excursion in ICR mouse assessed as glucose AUC (0 to 120 mins) at 15 mg/kg administered as single dose by oral glucose tolerance test (Rvb = 1175.5 +/- 216.4 mmol/L/min) Mus musculus 3 ALA3351537 organism-based format Scientific Literature 10. ALA3370164 Functional Reduction in glucose excursion in ICR mouse compound administered as single dose measured at 15 mins post dose by oral glucose tolerance test Mus musculus 2 ALA3351537 organism-based format Scientific Literature 11. ALA3370165 Functional Reduction in glucose AUC (0 to 120 mins) in C57BKS db/db mouse at 15 mg/kg/day, po for 5 weeks by oral glucose tolerance test (Rvb = 3649.5 +/- 91.5mmol/L/min) Mus musculus 2 ALA3351537 organism-based format Scientific Literature 12. ALA3370166 Functional Reduction in fasting blood glucose level in C57BKS db/db mouse at 15 mg/kg/day, po (Rvb =23.0 +/- 1.0 mM) Mus musculus 2 ALA3351537 organism-based format Scientific Literature 13. ALA3370167 Functional Reduction in plasma triglyceride content in C57BKS db/db mouse at 15 mg/kg/day, po (Rvb = 1.01 +/- 0.09 mM) Mus musculus 2 ALA3351537 organism-based format Scientific Literature 14. ALA3370168 Functional Reduction in free fatty acid in C57BKS db/db mouse at 15 mg/kg/day, po (Rvb = 1.46 +/- 0.10 mM) Mus musculus 2 ALA3351537 organism-based format Scientific Literature 15. ALA3370169 Functional Increase in basal plasma insulin content in C57BKS db/db mouse at 15 mg/kg/day, po relative to control Mus musculus 2 ALA3351537 organism-based format Scientific Literature 16. ALA3370170 Functional Reduction in random blood glucose level in C57BKS db/db mouse at 15 mg/kg/day, po (Rvb =23.3 +/- 1.0 mM) Mus musculus 2 ALA3351537 organism-based format Scientific Literature 17. ALA3370171 Functional Reduction in total cholesterol content in C57BKS db/db mouse at 15 mg/kg/day, po Mus musculus 2 ALA3351537 organism-based format Scientific Literature 18. ALA3370178 ADME Tmax in Sprague-Dawley rat at 20 mg/kg, po Rattus norvegicus 1 ALA3351537 organism-based format Scientific Literature 19. ALA3370180 ADME Cmax in Sprague-Dawley rat at 20 mg/kg, po Rattus norvegicus 1 ALA3351537 organism-based format Scientific Literature 20. ALA3370181 ADME AUC (0 to t) in Sprague-Dawley rat at 20 mg/kg, po Rattus norvegicus 1 ALA3351537 organism-based format Scientific Literature