# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3388502 | A | Pro-drug conversion in pH 7.4 PBS solution assessed as oncrasin-72 release at 0.5 mg/ml by HPLC method | 1 | assay format | Scientific Literature | |||
2. | ALA3388503 | A | Pro-drug conversion in pH 7.4 PBS solution assessed as complete oncrasin-72 release measured after 6 hrs at 0.5 mg/ml by HPLC method | 1 | assay format | Scientific Literature | |||
3. | ALA3388504 | A | Pro-drug conversion in human plasma assessed as oncrasin-72 release by HPLC method | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
4. | ALA3388505 | F | Anticancer activity against human NCI-H157 cells at 0.03 to 30 uM by sulforhodamine B assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA3388506 | F | Anticancer activity against human H460 cells at 0.03 to 30 uM by sulforhodamine B assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA3388507 | F | Anticancer activity against human Calu3 cells at 0.03 to 30 uM by sulforhodamine B assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA3388508 | F | Anticancer activity against human H1299 cells at 0.03 to 30 uM by sulforhodamine B assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA3388510 | P | Stability in powder form in non-evacuated chambers at 37 degC after 1 to 14 days by HPLC method | 2 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA3388511 | P | Stability in powder form in non-evacuated chambers at room temperature by HPLC method | 1 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA3388512 | P | Stability in powder form in non-evacuated chambers at 4 degC by HPLC method | 1 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA3388513 | P | Stability in powder form in non-evacuated chambers at 37 degC by HPLC method | 1 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA3388514 | P | Stability in powder form in non-evacuated chambers at 37 degC after 90 days by HPLC method | 1 | small-molecule physicochemical format | Scientific Literature | |||
13. | ALA3388516 | P | Stability in stock solution with Solutol HS15 and ethyl alcohol solvent at room temperature by HPLC method | 2 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA3389094 | P | Stability in stock solution with Solutol HS15 and ethyl alcohol solvent at 4 degC by HPLC method | 1 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA3389095 | P | Stability in injectable solution with Solutol HS15 and ethyl alcohol and 0.9% NaCl assessed as drug hydrolysis within 7 hrs at room temperature by HPLC method | 2 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA3389096 | P | Stability in injectable solution with Solutol HS15 and ethyl alcohol and 0.9% NaCl assessed as drug hydrolysis within 7 hrs at 37 degC by HPLC method | 2 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA3389097 | A | Half life in Balb/c mouse at 25 mg/kg, iv using compound formulated in Solutol HS15 and ethyl alcohol by HPLC/MS method | Mus musculus | 2 | organism-based format | Scientific Literature | ||
18. | ALA3389098 | A | Half life in Balb/c mouse assessed as oncrasin-72 release at 25 mg/kg, iv using compound formulated in Solutol HS15 and ethyl alcohol by HPLC/MS method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
19. | ALA3390320 | A | Drug level in liver of Balb/c mouse xenografted with human Calu3 cells assessed as aldehyde metabolite level at 60 mg/kg, iv using compound formulated in Solutol HS15 and ethyl alcohol measured after 24 hrs by HPLC/MS method | Mus musculus | 2 | organism-based format | Scientific Literature | ||
20. | ALA3381200 | A | Drug level in lung of Balb/c mouse xenografted with human Calu3 cells assessed as aldehyde metabolite level at 60 mg/kg, iv using compound formulated in Solutol HS15 and ethyl alcohol measured after 24 hrs by HPLC/MS method | Mus musculus | 2 | organism-based format | Scientific Literature |