# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3384537 | Binding | Inhibition of Trypanosoma brucei GSK3 using biotinylated GSP2 substrate by flashplate assay | Trypanosoma brucei | 51 | ALA3352013 | assay format | Scientific Literature | |
2. | ALA3384538 | Binding | Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | Homo sapiens | 51 | ALA3352013 | protein format | Scientific Literature | |
3. | ALA3385151 | Binding | Selectivity ratio, ratio of IC50 for human GSK3 to IC50 Trypanosoma brucei GSK3 | 51 | ALA3352013 | assay format | Scientific Literature | ||
4. | ALA3385152 | Binding | Inhibition of human CDK2/cyclin A using Biotin-C6-PKTPKKAKKL substrate | Homo sapiens | 51 | ALA3352013 | protein complex format | Scientific Literature | |
5. | ALA3385153 | Binding | Selectivity ratio, ratio of IC50 for human CDK2/cyclin A to IC50 for Trypanosoma brucei GSK3 | 51 | ALA3352013 | assay format | Scientific Literature | ||
6. | ALA3385154 | Functional | Trypanocidal activity against bloodstream stage of Trypanosoma brucei brucei assessed as inhibition of proliferation after 72 hrs | Trypanosoma brucei brucei | 51 | ALA3352013 | organism-based format | Scientific Literature | |
7. | ALA3385155 | ADME | Cytotoxicity against human MRC5 cells assessed as growth inhibition after 72 hrs | Homo sapiens | 51 | ALA3352013 | cell-based format | Scientific Literature | |
8. | ALA3385156 | Binding | Inhibition of MKK1 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
9. | ALA3385157 | Binding | Inhibition of ERK2 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
10. | ALA3385158 | Binding | Inhibition of JNK1 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
11. | ALA3385159 | Binding | Inhibition of JNK2 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
12. | ALA3385160 | Binding | Inhibition of ERK8 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
13. | ALA3385161 | Binding | Inhibition of MAPKAP-K2 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
14. | ALA3385162 | Binding | Inhibition of GSK3b (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
15. | ALA3385163 | Binding | Inhibition of CDK2 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
16. | ALA3385164 | Binding | Inhibition of MELK (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
17. | ALA3385165 | Binding | Inhibition of DYRK1A (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
18. | ALA3385166 | Binding | Inhibition of DYRK2 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
19. | ALA3385167 | Binding | Inhibition of DYRK3 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature | |
20. | ALA3385168 | Binding | Inhibition of PIM1 (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 4 | ALA3352013 | single protein format | Scientific Literature |