# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3378918 | Binding | Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding potential of -80 mV by electrophysiology | Homo sapiens | 21 | ALA3352579 | assay format | Scientific Literature | |
2. | ALA3378919 | Binding | Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding potential of -80 mV by electrophysiology relative to control | Homo sapiens | 18 | ALA3352579 | assay format | Scientific Literature | |
3. | ALA3826204 | ADME | Growth inhibition of Streptococcus gordonii at 200 uM after 24 hrs | Streptococcus gordonii | 1 | ALA3822431 | organism-based format | Scientific Literature | |
4. | ALA3826205 | Unassigned | Selectivity index, ratio of biofilm inhibition IC50 for Streptococcus mutans UA159 to growth inhibition IC50 for Streptococcus mutans UA159 | Streptococcus mutans | 5 | ALA3822431 | organism-based format | Scientific Literature | |
5. | ALA3826206 | Functional | Inhibition of biofilm formation of Streptococcus mutans UA159 at 200 uM after 16 hrs by crystal violet staining | Streptococcus mutans | 14 | ALA3822431 | organism-based format | Scientific Literature | |
6. | ALA3826207 | ADME | Growth inhibition of Streptococcus mutans UA159 at 200 uM after 24 hrs | Streptococcus mutans | 14 | ALA3822431 | organism-based format | Scientific Literature | |
7. | ALA3826208 | Functional | Inhibition of biofilm formation of Streptococcus mutans UA159 after 16 hrs by crystal violet staining based serial dilution method | Streptococcus mutans | 8 | ALA3822431 | organism-based format | Scientific Literature | |
8. | ALA3826209 | ADME | Growth inhibition of Streptococcus mutans UA159 after 16 hrs | Streptococcus mutans | 8 | ALA3822431 | organism-based format | Scientific Literature | |
9. | ALA3826210 | Functional | Inhibition of biofilm formation of Streptococcus mutans UA159 at 25 to 100 uM by Syto9 staining based assay | Streptococcus mutans | 1 | ALA3822431 | organism-based format | Scientific Literature | |
10. | ALA3826211 | ADME | Growth inhibition of Streptococcus sanguinis SK36 at 200 uM after 24 hrs | Streptococcus sanguinis | 1 | ALA3822431 | assay format | Scientific Literature | |
11. | ALA3826212 | Binding | Inhibition of Wild-type Streptococcus mutans UA159 glucosyltransferase B at 50 uM by zymography | Streptococcus mutans UA159 | 5 | ALA3822431 | single protein format | Scientific Literature | |
12. | ALA3826213 | Binding | Inhibition of Wild-type Streptococcus mutans UA159 glucosyltransferase D at 50 uM by zymography | Streptococcus mutans UA159 | 5 | ALA3822431 | single protein format | Scientific Literature | |
13. | ALA3826214 | Binding | Inhibition of Wild-type Streptococcus mutans UA159 glucosyltransferase C at 50 uM by zymography | Streptococcus mutans UA159 | 5 | ALA3822431 | single protein format | Scientific Literature | |
14. | ALA3826215 | Binding | Inhibition of Wild-type Streptococcus mutans UA159 glucosyltransferase B at 50 uM by coomassie blue staining based SDS-PAGE method | Streptococcus mutans UA159 | 5 | ALA3822431 | single protein format | Scientific Literature | |
15. | ALA3826216 | Binding | Inhibition of Wild-type Streptococcus mutans UA159 glucosyltransferase D at 50 uM by coomassie blue staining based SDS-PAGE method | Streptococcus mutans UA159 | 5 | ALA3822431 | single protein format | Scientific Literature | |
16. | ALA3826217 | Binding | Inhibition of Wild-type Streptococcus mutans UA159 glucosyltransferase C at 50 uM by coomassie blue staining based SDS-PAGE method | Streptococcus mutans UA159 | 5 | ALA3822431 | single protein format | Scientific Literature | |
17. | ALA3826514 | Functional | Inhibition of Gfp tagged Streptococcus mutans UA159 colony formation in guts of sucrose-dependent Drosophila colonization model at 50 uM measured 7 days post infection by fluorescent microscopy | Streptococcus mutans | 2 | ALA3822431 | organism-based format | Scientific Literature | |
18. | ALA4199303 | Binding | Inhibition of recombinant human MIF at 100 uM using L-3,4-dihydroxyphenylalanine methyl ester as substrate preincubated for 15 mins followed by substrate addition measured after 5 mins | Homo sapiens | 1 | ALA4196100 | single protein format | Scientific Literature |