# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3381497 | P | Stability in pH 7.4 buffer solution | 3 | ALA3351963 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA3381498 | P | Retention time of the compound by HPLC method | 4 | ALA3351963 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA3381500 | P | Stability in presence of 1 mM reduced glutathione at 100 uM after 24 hrs at 37 degC by HPLC method | 1 | ALA3351963 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA3381501 | A | Stability in rat liver S9 fraction at 100 uM after 24 hrs in absence of 1 mM reduced glutathione at 37 degC by HPLC method | Rattus norvegicus | 1 | ALA3351963 | assay format | Scientific Literature | |
5. | ALA3381502 | A | Prodrug conversion in rat liver S9 fraction assessed as half life for metformin formation at 100 uM in presence of 1 mM reduced glutathione by HPLC method | Rattus norvegicus | 1 | ALA3351963 | subcellular format | Scientific Literature | |
6. | ALA3381503 | A | Prodrug conversion in rat liver microsomes assessed as half life for metformin formation at 100 uM in presence of a NADPH-regenerating system by HPLC method | Rattus norvegicus | 1 | ALA3351963 | assay format | Scientific Literature | |
7. | ALA3381504 | A | Prodrug conversion in rat liver cytosol assessed as half life for metformin formation at 100 uM in presence of a NADPH-regenerating system by HPLC method | Rattus norvegicus | 1 | ALA3351963 | tissue-based format | Scientific Literature | |
8. | ALA3381505 | A | Prodrug conversion in human liver S9 fraction assessed as half life for metformin formation at 100 uM in presence of 1 mM reduced glutathione by HPLC method | Homo sapiens | 1 | ALA3351963 | subcellular format | Scientific Literature | |
9. | ALA3381506 | A | Prodrug conversion assessed as half life for human recombinant GST-A1-mediated metformin formation at 100 uM in presence of 1 mM reduced glutathione by HPLC method | Homo sapiens | 1 | ALA3351963 | single protein format | Scientific Literature | |
10. | ALA3381507 | A | Prodrug conversion assessed as half life for human recombinant GST-M2-mediated metformin formation at 100 uM in presence of 1 mM reduced glutathione by HPLC method | Homo sapiens | 1 | ALA3351963 | single protein format | Scientific Literature | |
11. | ALA3381508 | A | Prodrug conversion assessed as half life for human recombinant GST-P1-mediated metformin formation at 100 uM in presence of 1 mM reduced glutathione by HPLC method | Homo sapiens | 1 | ALA3351963 | single protein format | Scientific Literature | |
12. | ALA3381509 | A | Prodrug conversion in rat liver S9 fraction assessed as half life for GST-mediated metformin formation at 10 to 200 uM in presence of 1 mM reduced glutathione by Michaelis-Menten method | Rattus norvegicus | 2 | ALA3351963 | subcellular format | Scientific Literature | |
13. | ALA3381510 | P | Distribution coefficient, logD of the compound in mixture of 1-octanol and 50 mM phosphate buffer pH 7.4 by HPLC method | 2 | ALA3351963 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA3381511 | P | Aqueous solubility in pure water incubated for 1 hr by HPLC based shake flask method | 1 | ALA3351963 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA3381512 | P | Stability in pH 1.0 HCl buffer solution measured over 3 weeks by HPLC method | 1 | ALA3351963 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA3381513 | A | Stability in rat small intestine homogenates by HPLC method | Rattus norvegicus | 1 | ALA3351963 | tissue-based format | Scientific Literature |