| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3390454 | B | Inhibition of HDAC in human HL60 cells assessed as increase in p21 expression at 50 uM after 24 hrs by flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3390455 | F | Induction of ROS generation in human HL60 cells at 2 and 5 mM after 24 hrs by DCFH-DA staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3390457 | P | Half life in pH 7.4 isotonic sodium phosphate buffer at 37 degC by HPLC-DAD-ESI-MS method | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA3390458 | A | Half life in RPMI-1640 medium containing 10% fetal calf serum assessed as compound disappearance by HPLC-DAD-ESI-MS method | Bos taurus | 5 | assay format | Scientific Literature | ||
| 5. | ALA3390461 | B | Inhibition of ribonucleotide reductase in human HL60 cells assessed as intracellular dNTP pools level at 50 uM after 1 hr by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3390463 | B | Inhibition of human recombinant ribonucleotide reductase at 0.1 mM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 7. | ALA3381362 | F | Induction of cell cycle arrest in human HL60 cells assessed as accumulation at G1 phase at 50 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 32%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3381363 | F | Induction of cell cycle arrest in human HL60 cells assessed as accumulation at S phase at 50 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 54%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3381364 | F | Induction of cell cycle arrest in human HL60 cells assessed as accumulation at G2M phase at 50 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 12%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3373491 | F | Induction of apoptosis in human HL60 cells after 24 to 48 hrs by acridine orange and ethidium bromide staining based fluorescence microscopy | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA3373496 | F | Growth inhibition of human HL60 cells after 48 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA3373497 | F | Growth inhibition of human K562 cells after 48 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 13. | ALA3373498 | F | Growth inhibition of human HUT78 cells after 48 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 14. | ALA3373499 | F | Growth inhibition of human HT-29 cells after 48 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 15. | ALA3373500 | F | Growth inhibition of human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 16. | ALA3373501 | F | Growth inhibition of human HeLa cells after 48 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 17. | ALA3373502 | F | Growth inhibition of human Caco2 cells after 48 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 18. | ALA3373503 | B | Inhibition of HDAC in human HL60 cells assessed as increase in histone H3 acetylation at 10 and 100 uM after 24 hrs by Western blotting method | Homo sapiens | 2 | cell-based format | Scientific Literature |
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