# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3390457 | P | Half life in pH 7.4 isotonic sodium phosphate buffer at 37 degC by HPLC-DAD-ESI-MS method | 3 | ALA3351354 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA3390458 | A | Half life in RPMI-1640 medium containing 10% fetal calf serum assessed as compound disappearance by HPLC-DAD-ESI-MS method | Bos taurus | 5 | ALA3351354 | assay format | Scientific Literature | |
3. | ALA3390460 | B | Inhibition of ribonucleotide reductase in human HL60 cells assessed as intracellular dNTP pools level at 0.3 mM after 1 hr by HPLC method | Homo sapiens | 1 | ALA3351354 | cell-based format | Scientific Literature | |
4. | ALA3390462 | B | Inhibition of human recombinant ribonucleotide reductase at 1.2 mM | Homo sapiens | 2 | ALA3351354 | protein complex format | Scientific Literature | |
5. | ALA3390464 | B | Inhibition of human recombinant ribonucleotide reductase at 1.2 mM in presence of 1 mM ATP | Homo sapiens | 1 | ALA3351354 | protein complex format | Scientific Literature | |
6. | ALA3390465 | B | Inhibition of human recombinant ribonucleotide reductase at 1.2 mM in presence of 3 mM ATP | Homo sapiens | 1 | ALA3351354 | protein complex format | Scientific Literature | |
7. | ALA3390466 | B | Inhibition of human recombinant ribonucleotide reductase at 1.2 mM in presence of dGTP | Homo sapiens | 1 | ALA3351354 | protein complex format | Scientific Literature | |
8. | ALA3390467 | B | Competitive inhibition of human recombinant ribonucleotide reductase in presence of varying levels of ATP by Dixon plot | Homo sapiens | 1 | ALA3351354 | protein complex format | Scientific Literature | |
9. | ALA3381365 | F | Induction of cell cycle arrest in human HL60 cells assessed as accumulation at G1 phase at 100 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 32%) | Homo sapiens | 1 | ALA3351354 | cell-based format | Scientific Literature | |
10. | ALA3381366 | F | Induction of cell cycle arrest in human HL60 cells assessed as accumulation at S phase at 100 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 54%) | Homo sapiens | 1 | ALA3351354 | cell-based format | Scientific Literature | |
11. | ALA3381367 | F | Induction of cell cycle arrest in human HL60 cells assessed as accumulation at G2M phase at 100 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 12%) | Homo sapiens | 1 | ALA3351354 | cell-based format | Scientific Literature | |
12. | ALA3373491 | F | Induction of apoptosis in human HL60 cells after 24 to 48 hrs by acridine orange and ethidium bromide staining based fluorescence microscopy | Homo sapiens | 5 | ALA3351354 | cell-based format | Scientific Literature | |
13. | ALA3373496 | F | Growth inhibition of human HL60 cells after 48 hrs by MTT assay | Homo sapiens | 6 | ALA3351354 | cell-based format | Scientific Literature | |
14. | ALA3373497 | F | Growth inhibition of human K562 cells after 48 hrs by MTT assay | Homo sapiens | 6 | ALA3351354 | cell-based format | Scientific Literature | |
15. | ALA3373498 | F | Growth inhibition of human HUT78 cells after 48 hrs by MTT assay | Homo sapiens | 6 | ALA3351354 | cell-based format | Scientific Literature | |
16. | ALA3373499 | F | Growth inhibition of human HT-29 cells after 48 hrs by MTT assay | Homo sapiens | 6 | ALA3351354 | cell-based format | Scientific Literature | |
17. | ALA3373500 | F | Growth inhibition of human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 6 | ALA3351354 | cell-based format | Scientific Literature | |
18. | ALA3373501 | F | Growth inhibition of human HeLa cells after 48 hrs by MTT assay | Homo sapiens | 6 | ALA3351354 | cell-based format | Scientific Literature | |
19. | ALA3373502 | F | Growth inhibition of human Caco2 cells after 48 hrs by MTT assay | Homo sapiens | 6 | ALA3351354 | cell-based format | Scientific Literature | |
20. | ALA3373503 | B | Inhibition of HDAC in human HL60 cells assessed as increase in histone H3 acetylation at 10 and 100 uM after 24 hrs by Western blotting method | Homo sapiens | 2 | ALA3351354 | cell-based format | Scientific Literature |