# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3366750 | B | Inhibition of HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells after 6 to 8 hrs by luciferase assay | Human immunodeficiency virus 1 | 21 | ALA3351900 | cell-based format | Scientific Literature | |
2. | ALA3366751 | F | Antiviral activity against HIV1 3B infected in human MT2 cells assessed as inhibition of viral p24 antigen production by ELISA | Human immunodeficiency virus 1 | 15 | ALA3351900 | organism-based format | Scientific Literature | |
3. | ALA3366752 | A | Cytotoxicity against human MT2 cells after 4 days by XTT assay | Homo sapiens | 15 | ALA3351900 | cell-based format | Scientific Literature | |
4. | ALA3366753 | F | Antiviral activity against HIV1 BaL infected in human MT2 cells assessed as inhibition of viral replication | Human immunodeficiency virus 1 | 15 | ALA3351900 | organism-based format | Scientific Literature | |
5. | ALA3366754 | T | Selectivity index, ratio of CC50 for human MT2 cells to EC50 for HIV1 3B infected in human MT2 cells | 15 | ALA3351900 | cell-based format | Scientific Literature | ||
6. | ALA3366758 | B | Inhibition of HIV1 gp41 NHR assessed as inhibition of 6HB formation by FRET assay | Human immunodeficiency virus 1 | 8 | ALA3351900 | single protein format | Scientific Literature | |
7. | ALA3361460 | P | Solubility of the compound in pure water by UV spectrophotometry | 2 | ALA3351900 | small-molecule physicochemical format | Scientific Literature |