# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3388594 | B | Inhibition of human recombinant mPGES-1 expressed in CHO cells using PGH2 as substrate incubated for 10 mins prior to substrate addition measured after 1 min | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
2. | ALA3389824 | B | Inhibition of mPGES-1 in human A549 cells assessed as inhibition of IL-1beta-induced PGE2 production incubated for 30 mins prior to IL-1beta challenge measured after 18 to 24 hrs | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA3389825 | B | Inhibition of mPGES-1 in human whole blood assessed as inhibition of LPS-induced PGE2 production after overnight incubation | Homo sapiens | 3 | single protein format | Scientific Literature | ||
4. | ALA3389826 | B | Inhibition of COX1 in human U937 cells at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA3389827 | B | Inhibition of recombinant COX2 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA3389828 | B | Inhibition of recombinant mPGES-2 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA3389829 | B | Inhibition of recombinant cPGES (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA3389830 | B | Inhibition of recombinant PGDS (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA3389831 | B | Inhibition of recombinant TXAS (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA3389832 | B | Inhibition of recombinant PGIS (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA3389833 | B | Induction of recombinant PGF2-alpha (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA3389834 | B | Inhibition of cPLA2 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA3389835 | B | Selectivity for human recombinant mPGES-1 over COX1 in human U937 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA3389836 | B | Selectivity for human recombinant mPGES-1 over recombinant COX2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
15. | ALA3389837 | B | Selectivity for human recombinant mPGES-1 over recombinant mPGES-2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
16. | ALA3389838 | B | Selectivity for human recombinant mPGES-1 over recombinant cPGES (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
17. | ALA3389839 | B | Selectivity for human recombinant mPGES-1 over PGI2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
18. | ALA3389840 | B | Selectivity for human recombinant mPGES-1 over PGD2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
19. | ALA3390394 | B | Selectivity for human recombinant mPGES-1 over TXA2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
20. | ALA3390395 | B | Inhibition of mPGES-1 in human synovial fibroblast from rheumatoid arthritis patient using PGH1 as substrate assessed as inhibition of IL-1beta-induced PGE2 formation | Homo sapiens | 1 | single protein format | Scientific Literature |