# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3390424 | Binding | Antagonist activity at alpha1A adrenoceptor in Wistar rat vas deferans assessed as noradrenaline-induced contractions after 30 mins | Rattus norvegicus | 27 | ALA3351355 | single protein format | Scientific Literature | |
2. | ALA3390425 | Binding | Antagonist activity at alpha1B adrenoceptor in Wistar rat spleen assessed as phenylephrine-induced contractions after 30 mins | Rattus norvegicus | 27 | ALA3351355 | single protein format | Scientific Literature | |
3. | ALA3390426 | Binding | Antagonist activity at alpha1D adrenoceptor in Wistar rat thoracic aorta assessed as noradrenaline-induced contractions after 30 mins | Rattus norvegicus | 27 | ALA3351355 | single protein format | Scientific Literature | |
4. | ALA3390427 | Binding | Selectivity ratio of Kb for alpha1D adrenoceptor in Wistar rat thoracic aorta to Kb for alpha1A adrenoceptor in Wistar rat vas deferans | Rattus norvegicus | 27 | ALA3351355 | tissue-based format | Scientific Literature | |
5. | ALA3390428 | Binding | Selectivity ratio of Kb for alpha1D adrenoceptor in Wistar rat thoracic aorta to Kb for alpha1B adrenoceptor in Wistar rat spleen | Rattus norvegicus | 27 | ALA3351355 | tissue-based format | Scientific Literature | |
6. | ALA3390429 | Binding | Selectivity ratio of Kb for alpha1B adrenoceptor in Wistar rat spleen to Kb for alpha1A adrenoceptor in Wistar rat vas deferans | Rattus norvegicus | 27 | ALA3351355 | tissue-based format | Scientific Literature | |
7. | ALA3390430 | Binding | Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting | Homo sapiens | 27 | ALA3351355 | cell-based format | Scientific Literature | |
8. | ALA3390431 | Binding | Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting | Homo sapiens | 27 | ALA3351355 | cell-based format | Scientific Literature | |
9. | ALA3381315 | Binding | Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting | Homo sapiens | 27 | ALA3351355 | cell-based format | Scientific Literature | |
10. | ALA3381316 | Binding | Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting | Homo sapiens | 27 | ALA3351355 | cell-based format | Scientific Literature | |
11. | ALA3381317 | Binding | Selectivity ratio of Ki for human recombinant alpha1D adrenoceptor expressed in CHO cells to Ki for human recombinant alpha1A adrenoceptor expressed in CHO cells | Homo sapiens | 27 | ALA3351355 | cell-based format | Scientific Literature | |
12. | ALA3381318 | Binding | Selectivity ratio of Ki for human recombinant alpha1D adrenoceptor expressed in CHO cells to Ki for human recombinant alpha1B adrenoceptor expressed in CHO cells | Homo sapiens | 27 | ALA3351355 | cell-based format | Scientific Literature | |
13. | ALA3381319 | Binding | Selectivity ratio of Ki for human recombinant alpha1B adrenoceptor expressed in CHO cells to Ki for human recombinant alpha1A adrenoceptor expressed in CHO cells | Homo sapiens | 27 | ALA3351355 | cell-based format | Scientific Literature | |
14. | ALA3381320 | Binding | Selectivity ratio of Ki for human recombinant 5-HT1A receptor expressed in HeLa cells to Ki for human recombinant alpha1A adrenoceptor expressed in CHO cells | Homo sapiens | 27 | ALA3351355 | cell-based format | Scientific Literature | |
15. | ALA3373363 | Functional | Agonist activity at human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by [35S]GTPgammaS binding assay | Homo sapiens | 13 | ALA3351355 | cell-based format | Scientific Literature | |
16. | ALA3373364 | Functional | Agonist activity at human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by [35S]GTPgammaS binding assay relative to control | Homo sapiens | 13 | ALA3351355 | cell-based format | Scientific Literature |