| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3381964 | B | Inhibition of human recombinant PARP1 incubated for 1 hr using histone substrate at 1 uM by luminescence based assay | Homo sapiens | 18 | ALA3351316 | single protein format | Scientific Literature | |
| 2. | ALA3381965 | B | Inhibition of human recombinant PARP2 incubated for 1 hr using histone substrate at 1 uM by luminescence based assay | Homo sapiens | 18 | ALA3351316 | single protein format | Scientific Literature | |
| 3. | ALA3381966 | B | Inhibition of GST-tagged human recombinant TNKS1 at 1 uM incubated for 1 hr using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 19 | ALA3351316 | single protein format | Scientific Literature | |
| 4. | ALA3381967 | B | Inhibition of GST-tagged human recombinant TNKS2 at 1 uM incubated for 1 hr using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 19 | ALA3351316 | single protein format | Scientific Literature | |
| 5. | ALA3381969 | P | Lipophilicity, log D of the compound at pH 7.4 | 18 | ALA3351316 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA3382564 | B | Inhibition of GST-tagged human recombinant TNKS1 incubated for 1 hr using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 5 | ALA3351316 | single protein format | Scientific Literature | |
| 7. | ALA3382565 | B | Inhibition of GST-tagged human recombinant TNKS2 incubated for 1 hr using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 5 | ALA3351316 | single protein format | Scientific Literature | |
| 8. | ALA3382566 | B | Inhibition of tankyrase in human DLD1 cells assessed as reduction in Wnt activity after 24 hrs by TCF-luciferase reporter gene assay | Homo sapiens | 3 | ALA3351316 | cell-based format | Scientific Literature | |
| 9. | ALA3382567 | B | Inhibition of human recombinant PARP1 incubated for 1 hr using histone substrate at 10 uM by luminescence based assay | Homo sapiens | 2 | ALA3351316 | single protein format | Scientific Literature | |
| 10. | ALA3382568 | B | Inhibition of human recombinant PARP2 incubated for 1 hr using histone substrate at 10 uM by luminescence based assay | Homo sapiens | 2 | ALA3351316 | single protein format | Scientific Literature | |
| 11. | ALA3382569 | F | Growth inhibition of human DLD1 cells at 1 uM to 10 uM | Homo sapiens | 1 | ALA3351316 | cell-based format | Scientific Literature | |
| 12. | ALA3382570 | F | Growth inhibition of Wnt-negative human RKO cells at 1 uM to 10 uM | Homo sapiens | 1 | ALA3351316 | cell-based format | Scientific Literature | |
| 13. | ALA3382571 | F | Growth inhibition of Wnt-negative human RKO cells at >10 uM | Homo sapiens | 1 | ALA3351316 | cell-based format | Scientific Literature | |
| 14. | ALA3382572 | B | Inhibition of human recombinant PARP3 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | ALA3351316 | single protein format | Scientific Literature | |
| 15. | ALA3382573 | B | Inhibition of human recombinant PARP6 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | ALA3351316 | single protein format | Scientific Literature | |
| 16. | ALA3382574 | B | Inhibition of human recombinant PARP7 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | ALA3351316 | single protein format | Scientific Literature | |
| 17. | ALA3382575 | B | Inhibition of human recombinant PARP8 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | ALA3351316 | single protein format | Scientific Literature | |
| 18. | ALA3382576 | B | Inhibition of human recombinant PARP10 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | ALA3351316 | single protein format | Scientific Literature | |
| 19. | ALA3382577 | B | Inhibition of human recombinant PARP11 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | ALA3351316 | single protein format | Scientific Literature | |
| 20. | ALA3382578 | B | Inhibition of human recombinant PARP12 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | ALA3351316 | single protein format | Scientific Literature |
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