# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3375523 | A | Cytotoxicity against human HepG2 cells assessed as cell death after 48 hrs by Cell Titer-Glo assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
2. | ALA3370434 | B | Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrate | Plasmodium falciparum | 28 | single protein format | Scientific Literature | ||
3. | ALA3370435 | B | Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrate | Homo sapiens | 28 | single protein format | Scientific Literature | ||
4. | ALA3370436 | B | Inhibition of human BACE1 assessed as cleavage of TRF substrate | Homo sapiens | 28 | single protein format | Scientific Literature | ||
5. | ALA3370439 | B | Inhibition of Plasmodium vivax plasmepsin V by fluorogenic PEXEL cleavage assay | Plasmodium vivax | 1 | single protein format | Scientific Literature | ||
6. | ALA3370440 | B | Selectivity ratio of IC50 for human Cathepsin D to IC50 for Plasmodium falciparum plasmepsin V | 2 | assay format | Scientific Literature | |||
7. | ALA3370441 | F | Antiplasmodial activity against Plasmodium falciparum 3D7 infected in human O positive erythrocyte after 72 hrs | Plasmodium falciparum | 9 | organism-based format | Scientific Literature | ||
8. | ALA3370442 | B | Inhibition of plasmepsin V in Plasmodium falciparum trophozoite expressing PfEMP3-GFP infected erythrocyte assessed as PEXEL processing at 20 uM by immunoblotting analysis | Plasmodium falciparum | 9 | single protein format | Scientific Literature | ||
9. | ALA4271800 | B | Inhibition of recombinant Plasmodium vivax plasmepsin 5 expressed in High five insect cells using DABCYLRNKRTLAQKQ-E-EDANS as substrate measured after 120 mins by fluorescence assay | Plasmodium vivax | 24 | cell-based format | Scientific Literature | ||
10. | ALA4271804 | F | Antiplasmodial activity against ring-stage Plasmodium falciparum 3D7 assessed as reduction in parasite viability after 72 hrs by LDH assay | Plasmodium falciparum | 26 | organism-based format | Scientific Literature | ||
11. | ALA4271805 | F | Cytotoxicity against human HepG2 cells after 48 hrs by CellTiter-Glo assay | Homo sapiens | 27 | cell-based format | Scientific Literature |