| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3391091 | F | Antiviral activity against HIV1 NL4-3 harboring gp41 D36G mutant infected in human HeLa cells expressing CD4-LTR-beta-gal assessed as inhibition of viral replication after 48 hrs by MAGI assay | Human immunodeficiency virus 1 | 74 | organism-based format | Scientific Literature | ||
| 2. | ALA3391093 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N54-drug complex after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 37 | assay format | Scientific Literature | ||
| 3. | ALA3391094 | B | Thermal stability of HIV1 envelope glycoprotein gp41 His-tagged N-terminal heptad repeat N54-drug complex assessed as thermal unfolding transition state by measuring molar ellipticity at 4 to 90 degC by circular dichroic spectra analysis | Human immunodeficiency virus 1 | 37 | assay format | Scientific Literature | ||
| 4. | ALA3391099 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N54 V38A mutant-drug complex after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 5. | ALA3391100 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N54 N43D mutant-drug complex after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 6. | ALA3391101 | B | Thermal stability of HIV1 envelope glycoprotein gp41 His-tagged N-terminal heptad repeat N54 V38A mutant-drug complex assessed as thermal unfolding transition state by measuring molar ellipticity at 4 to 90 degC by circular dichroic spectra analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 7. | ALA3391102 | B | Thermal stability of HIV1 envelope glycoprotein gp41 His-tagged N-terminal heptad repeat N54 N43D mutant-drug complex assessed as thermal unfolding transition state by measuring molar ellipticity at 4 to 90 degC by circular dichroic spectra analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature |
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