# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3391326 | B | Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation by chemiluminescence assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
2. | ALA3391327 | B | Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation by measuring H2O2 production by fluorescence assay in presence of superoxide dismutase | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
3. | ALA3391328 | B | Inhibition of full length human NOX1 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation by chemiluminescence assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
4. | ALA3391329 | B | Inhibition of full length human NOX4 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation by measuring H2O2 production by fluorescence assay in presence of superoxide dismutase | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
5. | ALA3391330 | B | Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
6. | ALA3391331 | B | Inhibition of bovine milk xanthine oxidase assessed as hypoxanthine-stimulated ROS generation by measuring H2O2 production at 25 to 50 uM by fluorescence assay | Bos taurus | 19 | single protein format | Scientific Literature | ||
7. | ALA3391333 | B | Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of lithium dodecyl sulphate-stimulated ROS generation preincubated for 15 mins followed by lithium dodecyl sulphate challenge by cell-free assay in presence of NADPH | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA3734235 | B | Inhibition of human Nox2 expressed in COS7 cells co-transfected with human p22-phox,p47phox and p67-phox assessed as inhibition of PMA-induced superoxide generation by L-012 chemiluminescence analysis | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
9. | ALA3734236 | B | Inhibition of human Nox2 expressed in COS7 cells co-transfected with human p22-phox,p47phox and p67-phox assessed as inhibition of PMA-induced H2O2 production by amplex red dye based fluorescence assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
10. | ALA3734237 | B | Inhibition of human Nox4 expressed in COS7 cells assessed as inhibition of PMA-induced H2O2 production by amplex red dye based fluorescence assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
11. | ALA3734238 | B | Inhibition of bovine xanthine-oxidase assessed as H2O2 production at 25 to 50 uM by amplex red dye based fluorescence assay | Bos taurus | 17 | single protein format | Patent Bioactivity Data | ||
12. | ALA3734240 | B | Inhibition of human Nox1 expressed in COS7 cells co-transfected with human NOXO1/NOXA1 assessed as inhibition of PMA-induced superoxide generation by L-012 chemiluminescence analysis | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
13. | ALA3734241 | B | Inhibition of Nox5 expressed in HEK cells assessed as inhibition of PMA/ionomycin-induced superoxide generation by L-012 chemiluminescence analysis | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
14. | ALA3734242 | B | Inhibition of Nox2 (unknown origin) | Homo sapiens | 2 | single protein format | Patent Bioactivity Data | ||
15. | ALA3734243 | B | Inhibition of human Nox2 expressed in COS7 cells co-transfected with human p22-phox,p47phox and p67-phox assessed as inhibition of LiDS-induced ROS generation in cell homogenate | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
16. | ALA3734244 | F | Inhibition of high-glucose-stimulated superoxide production in HPAEC cells at 25 uM measured after 24 hrs | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
17. | ALA3734245 | F | Inhibition of angiotensin-2-stimulated superoxide production in HPAEC cells at 25 uM measured after 24 hrs | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
18. | ALA3734246 | B | Inhibition of Nox2 (unknown origin) assessed as inhibition of PMA-induced Nox2 and p47-phox interaction by immunoprecipitation analysis | Homo sapiens | 2 | single protein format | Patent Bioactivity Data | ||
19. | ALA3734247 | B | Inhibition of human Nox2 expressed in COS7 cells co-transfected with human p22-phox,p47phox and p67-phox assessed as inhibition of PMA-induced ROS production at 10 uM | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
20. | ALA3734248 | B | Inhibition of human Nox1 expressed in COS7 cells co-transfected with human co-transfected with human NOXO1/NOXA1 assessed as inhibition of PMA-induced ROS production at 10 uM | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data |