# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA649026 | B | Binding affinity was determined based on the displacement of [125]r-ANF (99-126) from binding sites on bovine adrenal zona glomerulosa cell membranes (Atrionatriuretic peptide receptor B) | 10 | assay format | Scientific Literature | |||
2. | ALA649027 | B | Binding affinity was determined based on the displacement of [125]r-ANF (99-126) from binding sites on mouse fibroblasts (NIH 3T3) cells (Atrionatriuretic peptide receptor C). | 10 | assay format | Scientific Literature | |||
3. | ALA770831 | F | Compound was tested for the inhibition of the stimulated contractions of the superfused rabbit thoracic aortic rings. | Oryctolagus cuniculus | 10 | organism-based format | Scientific Literature | ||
4. | ALA787667 | F | Compound was tested for antihypertensive activity in 5/6 nephrectomized rats. | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
5. | ALA787668 | F | Compound was tested for antihypertensive activity in DOCA nephrectomized rats. | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
6. | ALA782945 | F | Compound was tested for the Cl- excretion for treated over control animals | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
7. | ALA782948 | F | Compound was tested for the K+ excretion for treated over control animals | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
8. | ALA782951 | F | Compound was tested for the Na+ excretion for treated over control animals | Rattus norvegicus | 6 | organism-based format | Scientific Literature | ||
9. | ALA793466 | F | Compound was tested for diuretic activity and the ratio of urine volume for treated over control animals was reported after infused at a dose of 0.5 ug/kg. | Rattus norvegicus | 9 | organism-based format | Scientific Literature |