# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1953929 | P | Chemical stability of the compound in aqueous buffer at pH 2 assessed as decomposition at 5 mM up to 2 hrs by RP-HPLC | 8 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA1953930 | P | Chemical stability of the compound in aqueous buffer at pH 2 assessed as decomposition at 5 mM after 24 hrs by RP-HPLC | 8 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA1953931 | P | Chemical stability of the compound in aqueous buffer at pH 6 assessed as decomposition at 5 mM up to 2 hrs by RP-HPLC | 8 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA1953932 | P | Chemical stability of the compound in aqueous buffer at pH 6 assessed as decomposition at 5 mM after 24 hrs by RP-HPLC | 8 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA1953933 | P | Chemical stability of the compound in aqueous buffer at pH 8 assessed as decomposition at 5 mM up to 2 hrs by RP-HPLC | 8 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA1953934 | P | Chemical stability of the compound in aqueous buffer at pH 8 assessed as decomposition at 5 mM after 24 hrs by RP-HPLC | 8 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA1953935 | P | Stability of the compound at -20 degreeC after 12 months | 8 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA1953936 | B | Binding affinity to recombinant eIF4E by fluorescence quenching titration method | 14 | single protein format | Scientific Literature | |||
9. | ALA1953938 | A | Stability of the compound assessed as human recombinant DcpS -mediated hydrolysis after 2 hrs by HPLC | 8 | assay format | Scientific Literature | |||
10. | ALA1953940 | B | Binding affinity to human recombinant DcpS by fluorescence quenching titration method | Homo sapiens | 13 | single protein format | Scientific Literature | ||
11. | ALA1953941 | B | Selectivity ratio of Ka for human recombinant DcpS to Ka for eIF4E | Homo sapiens | 9 | assay format | Scientific Literature | ||
12. | ALA1953942 | B | Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assay | Oryctolagus cuniculus | 6 | assay format | Scientific Literature | ||
13. | ALA1953943 | B | Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate pre-incubated for 60 mins prior to mRNA addition by luciferase reporter gene assay | Oryctolagus cuniculus | 6 | assay format | Scientific Literature |