# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1023603 | Binding | Binding affinity to mouse eukaryotic initiation factor 4E expressed in Escherichia coli BL21(DE3) by fluorescence quenching titration method | Mus musculus | 6 | ALA1151839 | assay format | Scientific Literature | |
2. | ALA1023604 | ADME | Stability in presence of human DcpS assessed as complete degradation at 40 uM by HPLC-based assay | 6 | ALA1151839 | assay format | Scientific Literature | ||
3. | ALA1023605 | Binding | Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-capped 5'UTRbetaglob-LUC mRNA translation by luciferase-based luminometry | Oryctolagus cuniculus | 6 | ALA1151839 | assay format | Scientific Literature | |
4. | ALA1023606 | Binding | Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-capped 5'UTRbetaglob-LUC mRNA translation treated 60 mins before mRNA addition by luciferase-based luminometry | Oryctolagus cuniculus | 6 | ALA1151839 | assay format | Scientific Literature | |
5. | ALA1023607 | Binding | Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of rabbit beta-globulin mRNA translation by [3H]leucine incorporation assay | Oryctolagus cuniculus | 4 | ALA1151839 | assay format | Scientific Literature |