| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA646225 | B | Effective concentration in vitro against rat spleen Alpha-1B adrenergic receptor (EC50 < 15%) at a concentration of 10 uM; NA is not active | 1 | ALA1135819 | tissue-based format | Scientific Literature | ||
| 2. | ALA859406 | F | Antagonistic activity against Alpha-1B adrenergic receptor determined using phenylephrine challenge in rat spleen isolated tissues. | 1 | ALA1135819 | tissue-based format | Scientific Literature | ||
| 3. | ALA646234 | F | Functional agonism of the compounds to constrict tissue containing the alpha-1B adrenergic receptor in rat spleen. | 19 | ALA1148329 | tissue-based format | Scientific Literature | ||
| 4. | ALA645998 | B | Binding affinity towards rat cloned Alpha-1D adrenergic receptor; value ranges from (0.24 -0.32) | 1 | ALA1135819 | single protein format | Scientific Literature | ||
| 5. | ALA646004 | B | Effective concentration in vitro against rat aorta Alpha-1D adrenergic receptor (EC50 < 15%) at a concentration of 10 uM; NA is not active | 1 | ALA1135819 | tissue-based format | Scientific Literature | ||
| 6. | ALA646005 | F | Antagonistic activity against Alpha-1D adrenergic receptor determined using phenylephrine challenge in rat aorta isolated tissues. | 1 | ALA1135819 | tissue-based format | Scientific Literature | ||
| 7. | ALA648011 | B | In vitro binding affinity towards alpha-1D adrenergic receptor of rat clone in radioligand binding assay | 52 | ALA1148329 | single protein format | Scientific Literature | ||
| 8. | ALA643232 | B | In vitro binding affinity towards alpha-2A adrenergic receptor of human clone in radioligand binding assay | 15 | ALA1148329 | single protein format | Scientific Literature | ||
| 9. | ALA643882 | F | Efficacy relative to phenylephrine (PE) to constrict tissue containing the alpha-2A adrenergic receptor in rat prostatic vas deferens | 11 | ALA1148329 | tissue-based format | Scientific Literature | ||
| 10. | ALA645786 | F | Functional agonism to constrict tissue containing alpha-2A adrenergic receptor in rat prostatic vas deferens | Rattus norvegicus | 10 | ALA1148329 | tissue-based format | Scientific Literature | |
| 11. | ALA644238 | B | Binding affinity towards rat submaxillary gland Alpha-1 adrenergic receptor; value ranges from (0.12 - 0.15) | 1 | ALA1135819 | single protein format | Scientific Literature | ||
| 12. | ALA857772 | B | In vitro binding affinity towards alpha-2B adrenergic receptor of rat neonatal lung in radioligand binding assay | 15 | ALA1148329 | single protein format | Scientific Literature | ||
| 13. | ALA645470 | B | Effective concentration in vitro against rabbit urethra Alpha-1A adrenergic receptor | Oryctolagus cuniculus | 1 | ALA1135819 | single protein format | Scientific Literature | |
| 14. | ALA645471 | F | Efficacy relative to phenylephrine (PE) to constrict tissue containing the alpha-1A adrenergic receptor in rabbit urethra | Oryctolagus cuniculus | 29 | ALA1148329 | tissue-based format | Scientific Literature | |
| 15. | ALA645473 | F | Functional agonism of the compounds to constrict tissue containing the alpha-1A adrenergic receptor in rabbit urethra | Oryctolagus cuniculus | 29 | ALA1148329 | tissue-based format | Scientific Literature | |
| 16. | ALA648415 | B | In vitro binding affinity towards alpha-1A adrenergic receptor of rat submaxillary gland in radioligand binding assay | 46 | ALA1148329 | single protein format | Scientific Literature | ||
| 17. | ALA649216 | B | Binding affinity towards hamster cloned Alpha-1B adrenergic receptor; value ranges from (0.76 -1.0) | Cricetulus griseus | 1 | ALA1135819 | single protein format | Scientific Literature | |
| 18. | ALA648102 | B | In vitro binding affinity towards alpha-1B adrenergic receptor of hamster clone in radioligand binding assay | Cricetulus griseus | 52 | ALA1148329 | single protein format | Scientific Literature | |
| 19. | ALA648634 | F | Dose corresponding to a 20 mmHg increase in mean arterial pressure (MAP) was determined in vivo in isoflurane anesthetized female beagles | Canis lupus familiaris | 4 | ALA1135819 | organism-based format | Scientific Literature | |
| 20. | ALA648635 | F | Dose corresponding to a 5 mmHg increase in Intraurethral pressure (IUP) was determined in vivo in isoflurane anesthetized female beagles | Canis lupus familiaris | 4 | ALA1135819 | organism-based format | Scientific Literature |
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