| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA723043 | F | Effective dose (sc) required for antinociceptive potency in vivo in the hotplate (HP) test in mice | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 2. | ALA723044 | F | Effective dose (sc) required for antinociceptive potency in vivo in the paraphenylquinone writhing (PPQ) test in mice | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 3. | ALA723045 | F | Effective dose (sc) required for antinociceptive potency in vivo in the tail-flick (TF) test in mice | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 4. | ALA741430 | F | In vivo antinociceptive activity was determined upon subcutaneous administration by hot plate assay | Mus musculus | 10 | organism-based format | Scientific Literature | ||
| 5. | ALA741431 | F | In vivo antinociceptive activity was determined upon subcutaneous administration in the mouse paraphenylquinone writhing test | Mus musculus | 8 | organism-based format | Scientific Literature | ||
| 6. | ALA741433 | F | In vivo antinociceptive activity was determined upon subcutaneous administration in the mouse tail-flick test | Mus musculus | 10 | organism-based format | Scientific Literature | ||
| 7. | ALA872675 | B | In vitro binding affinity at opioid receptor kappa 1 was determined in human CHO cells using [3H]U-69593 | 10 | cell-based format | Scientific Literature | |||
| 8. | ALA754883 | B | In vitro binding affinity at opioid receptor delta 1 was determined in C6 rat glioma cells using [3H]Ile5,6 deltorphin II | 10 | cell-based format | Scientific Literature | |||
| 9. | ALA758580 | B | In vitro binding affinity at opioid receptor mu 1 was determined in C6 rat glioma cells using [3H]DAMGO | 10 | cell-based format | Scientific Literature | |||
| 10. | ALA847400 | B | Selectivity ratio was determined | 10 | assay format | Scientific Literature | |||
| 11. | ALA828270 | B | Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranes | Rattus norvegicus | 10 | cell membrane format | Scientific Literature | ||
| 12. | ALA839712 | B | Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranes | Cavia porcellus | 10 | assay format | Scientific Literature | ||
| 13. | ALA839649 | B | Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranes | Rattus norvegicus | 10 | cell membrane format | Scientific Literature | ||
| 14. | ALA832435 | F | In vitro agonistic activity against opioid receptor mu of guinea pig ileum | Cavia porcellus | 9 | tissue-based format | Scientific Literature | ||
| 15. | ALA831911 | F | In vitro agonistic activity against opioid receptor delta of mouse vas deferens | Mus musculus | 9 | tissue-based format | Scientific Literature | ||
| 16. | ALA829114 | F | Relative agonistic activity against opioid receptor delta in mouse vas deferens and opioid receptor mu in guinea pig ileum | 9 | tissue-based format | Scientific Literature | |||
| 17. | ALA829653 | B | Ratio of binding affinities for opioid receptors delta and mu | Rattus norvegicus | 10 | protein format | Scientific Literature | ||
| 18. | ALA829654 | B | Ratio of binding affinities for opioid receptors kappa and mu | 10 | assay format | Scientific Literature | |||
| 19. | ALA836513 | F | Antinociceptive potencie was assessed after subcutaneous administration of compound by hotplate test (HP) in mice | Mus musculus | 9 | organism-based format | Scientific Literature | ||
| 20. | ALA834571 | F | Gastrointestinal (GI) motility was assessed by colonic bead expulsion after subcutaneous administration in mice; Not tested | Mus musculus | 1 | organism-based format | Scientific Literature |
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