# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3364610 | B | Inhibition of human N-terminal GST-tagged PLK4 (1 to 391 residues) expressed in Escherichia coli incubated for 30 mins by ELISA method | Homo sapiens | 30 | ALA3351767 | assay format | Scientific Literature | |
2. | ALA3364611 | B | Inhibition of FLT3 (unknown origin) by FRET-based homogeneous assay | Homo sapiens | 17 | ALA3351767 | single protein format | Scientific Literature | |
3. | ALA3364612 | B | Inhibition of KDR (unknown origin) by FRET-based homogeneous assay | Homo sapiens | 17 | ALA3351767 | single protein format | Scientific Literature | |
4. | ALA3364613 | A | Inhibition of CYP1A2 (unknown origin) using CEC substrate after 15 mins by fluorescence assay | Homo sapiens | 16 | ALA3351767 | single protein format | Scientific Literature | |
5. | ALA3364614 | A | Inhibition of CYP2C9 (unknown origin) using MFC substrate after 45 mins by fluorescence assay | Homo sapiens | 16 | ALA3351767 | single protein format | Scientific Literature | |
6. | ALA3364615 | A | Inhibition of CYP2C19 (unknown origin) using MFC substrate after 30 mins by fluorescence assay | Homo sapiens | 16 | ALA3351767 | single protein format | Scientific Literature | |
7. | ALA3364616 | A | Inhibition of CYP2D6 (unknown origin) using AMMC substrate after 45 mins by fluorescence assay | Homo sapiens | 16 | ALA3351767 | single protein format | Scientific Literature | |
8. | ALA3364617 | A | Inhibition of CYP3A4 (unknown origin) using BFC substrate after 30 mins by fluorescence assay | Homo sapiens | 16 | ALA3351767 | single protein format | Scientific Literature | |
9. | ALA3364618 | F | Cytotoxicity against human MCF7 cells after 5 days by SRB assay | Homo sapiens | 29 | ALA3351767 | cell-based format | Scientific Literature | |
10. | ALA3364619 | F | Cytotoxicity against human MDA-MB-468 cells after 5 days by SRB assay | Homo sapiens | 29 | ALA3351767 | cell-based format | Scientific Literature | |
11. | ALA3364620 | P | Aqueous solubility at pH 7.4 | 8 | ALA3351767 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA3364621 | A | Protein binding in plasma (unknown origin) | Not specified | 8 | ALA3351767 | cell-free format | Scientific Literature | |
13. | ALA3364622 | A | Half life in mouse liver microsomes at 1 uM in presence of NADPH by LC-MS method | Mus musculus | 8 | ALA3351767 | assay format | Scientific Literature | |
14. | ALA3364623 | A | Half life in human liver microsomes at 1 uM in presence of NADPH by LC-MS method | Homo sapiens | 8 | ALA3351767 | assay format | Scientific Literature | |
15. | ALA3364624 | A | Cmax in SCID mouse at 50 mg/kg, ip after 8 hrs by LCMS/MS method | Mus musculus | 8 | ALA3351767 | organism-based format | Scientific Literature | |
16. | ALA3364625 | A | AUC in SCID mouse at 50 mg/kg, ip after 8 hrs by LCMS/MS method | Mus musculus | 8 | ALA3351767 | organism-based format | Scientific Literature | |
17. | ALA3364629 | F | Cytotoxicity against human MDA-MB-231 cells after 5 days by SRB assay | Homo sapiens | 26 | ALA3351767 | cell-based format | Scientific Literature | |
18. | ALA3364630 | F | Cytotoxicity against human SKBR3 cells after 5 days by SRB assay | Homo sapiens | 26 | ALA3351767 | cell-based format | Scientific Literature | |
19. | ALA3411381 | B | Inhibition of PLK4 (unknown origin) by ELISA | Homo sapiens | 27 | ALA3407349 | single protein format | Scientific Literature | |
20. | ALA3411382 | F | Growth inhibition of human MDA-MB-468 cells after 5 days by SRB assay | Homo sapiens | 27 | ALA3407349 | cell-based format | Scientific Literature |