| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3389322 | F | Neuroprotective effect in Sprague-Dawley rat DA neurons at 100 uM after 10 days by immunofluorescence assay | Rattus norvegicus | 1 | ALA3352059 | assay format | Scientific Literature | |
| 2. | ALA3389323 | F | Neuroprotective effect in Sprague-Dawley rat DA neurons assessed as [3H]-DA uptake at 100 uM after 10 days by liquid scintillation spectrometry relative to control | Rattus norvegicus | 1 | ALA3352059 | assay format | Scientific Literature | |
| 3. | ALA3389324 | F | Neuroprotective effect in Sprague-Dawley rat DA neurons assessed as developement of neuritic network at 100 uM after 10 days by microscopic analysis relative to control | Rattus norvegicus | 1 | ALA3352059 | assay format | Scientific Literature | |
| 4. | ALA3389331 | P | Aqueous solubility of the compound at pH 7.4 after 5 mins by HPLC analysis | 2 | ALA3352059 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA3389332 | T | Toxicity in C57BL/6J mouse assessed as behavioral change at 150 mg/kg, po bid administered for 4 days followed by single dose on day 5 by HPLC-MS/MS analysis | Mus musculus | 1 | ALA3352059 | organism-based format | Scientific Literature | |
| 6. | ALA3389333 | T | Toxicity in C57BL/6J mouse assessed as change in food intake at 150 mg/kg, po bid administered for 4 days followed by single dose on day 5 by HPLC-MS/MS analysis | Mus musculus | 1 | ALA3352059 | organism-based format | Scientific Literature | |
| 7. | ALA3389334 | T | Toxicity in C57BL/6J mouse assessed as change in body weight at 150 mg/kg, po bid administered for 4 days followed by single dose on day 5 by HPLC-MS/MS analysis | Mus musculus | 1 | ALA3352059 | organism-based format | Scientific Literature | |
| 8. | ALA3389335 | A | Drug uptake in C57BL/6J mouse brain at 150 mg/kg, po bid administered for 4 days followed by single dose on day 5 measured 1 hr post last dose | Mus musculus | 1 | ALA3352059 | organism-based format | Scientific Literature | |
| 9. | ALA3389336 | A | Ratio of drug uptake from brain to plasma in C57BL/6J mouse at 150 mg/kg, po bid administered for 4 days followed by single dose on day 5 measured 1 hr post last dose | Mus musculus | 1 | ALA3352059 | organism-based format | Scientific Literature | |
| 10. | ALA3383322 | A | Drug uptake in C57BL/6J mouse brain at 75 mg/kg, po after 1 hr by MALDI-TOF mass spectrometry | Mus musculus | 1 | ALA3352059 | organism-based format | Scientific Literature | |
| 11. | ALA3383323 | A | Drug uptake in C57BL/6J mouse striatum at 75 mg/kg, po after 1 hr by MALDI-TOF mass spectrometry | Mus musculus | 1 | ALA3352059 | organism-based format | Scientific Literature | |
| 12. | ALA3383324 | A | Ratio of drug uptake in C57BL/6J mouse striatum to cortical area at 75 mg/kg, po after 1 hr by MALDI-TOF mass spectrometry | Mus musculus | 1 | ALA3352059 | organism-based format | Scientific Literature | |
| 13. | ALA3383325 | A | Drug uptake in C57BL/6J mouse ventral mesencephalon at 75 mg/kg, po after 1 hr by MALDI-TOF mass spectrometry | Mus musculus | 1 | ALA3352059 | organism-based format | Scientific Literature | |
| 14. | ALA3383326 | F | Antiproliferative activity at Sprague-Dawley rat DA neurons assessed as reduction of [3H]-thymidine incorporation at 50 to 100 uM after 8 days by liquid scintillation spectrometry | Rattus norvegicus | 1 | ALA3352059 | assay format | Scientific Literature | |
| 15. | ALA3383328 | F | Neuroprotective effect in Sprague-Dawley rat DA neurons at 100 uM in presence of anti-GDNF antibody AB-212-NA | Rattus norvegicus | 1 | ALA3352059 | assay format | Scientific Literature | |
| 16. | ALA3383329 | F | Neuroprotective effect in Sprague-Dawley rat DA neurons under GDNF deprived condition at 50 to 100 uM | Rattus norvegicus | 1 | ALA3352059 | assay format | Scientific Literature | |
| 17. | ALA3383330 | P | Antioxidant activity assessed as radical scavenging activity after 1 hr by ABTS competition assay | 2 | ALA3352059 | small-molecule physicochemical format | Scientific Literature | ||
| 18. | ALA3383331 | F | Neuroprotective effect in Sprague-Dawley rat DA neurons under chronic oxidative stress condition | Rattus norvegicus | 1 | ALA3352059 | assay format | Scientific Literature | |
| 19. | ALA3383332 | F | Neuroprotective effect in Sprague-Dawley rat DA neurons at 10 uM under chronic oxidative stress condition | Rattus norvegicus | 2 | ALA3352059 | assay format | Scientific Literature | |
| 20. | ALA4431908 | F | Neuroprotective activity in Sprague-Dawley rat DA neuron death PD model assessed as survival of Th immunopositive cells at 100 uM after 10 days by immunofluorescence assay relative to control | Rattus norvegicus | 1 | ALA4431316 | assay format | Scientific Literature |
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