# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3375790 | B | Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
2. | ALA3375791 | B | Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA3375792 | F | Inhibition of IL2 production in activated mouse lymphocytes after 3 hrs by ELISA | Mus musculus | 18 | cell-based format | Scientific Literature | ||
4. | ALA3375793 | B | Selectivity ratio of IC50 for human PDE4B1 expressed in insect cells to IC50 for human PDE7A1 expressed in insect cell | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA3375794 | B | Selectivity ratio of IC50 for PDE3 (unknown origin) to IC50 for human PDE7A1 expressed in insect cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA3375795 | B | Selectivity ratio of IC50 for PDE5 (unknown origin) to IC50 for human PDE7A1 expressed in insect cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA3375796 | A | Stability in human liver microsomes | Homo sapiens | 3 | assay format | Scientific Literature | ||
8. | ALA3375797 | A | Stability in rat liver microsomes | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
9. | ALA3375798 | A | Permeability of the compound by PAMPA | 3 | assay format | Scientific Literature | |||
10. | ALA3374135 | B | Inhibition of PDE7A (unknown origin) | Homo sapiens | 22 | single protein format | Scientific Literature |