# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3386287 | Binding | Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometry | Homo sapiens | 5 | ALA3352753 | single protein format | Scientific Literature | |
2. | ALA3386288 | Binding | Inhibition of purified thrombin (unknown origin) using chromogenic substrate S-2238 by spectrophotometry | Homo sapiens | 5 | ALA3352753 | single protein format | Scientific Literature | |
3. | ALA3386289 | Binding | Inhibition of purified trypsin (unknown origin) using chromogenic substrate S-2222 by spectrophotometry | Homo sapiens | 5 | ALA3352753 | protein format | Scientific Literature | |
4. | ALA3386290 | Functional | Anticoagulant activity in cynomolgus monkey plasma assessed as concentration required to double prothrombin time by coagulometry | Macaca fascicularis | 5 | ALA3352753 | cell-free format | Scientific Literature | |
5. | ALA3386291 | ADME | Permeability of the compound at pH 6.5 after 2 hrs by PAMPA | 5 | ALA3352753 | assay format | Scientific Literature | ||
6. | ALA3386294 | Functional | Ex vivo anticoagulant activity in cynomolgus monkey plasma at 1 mg/kg, po as single bolus dose measured after 5 mins post dose | Macaca fascicularis | 1 | ALA3352753 | organism-based format | Scientific Literature | |
7. | ALA3390520 | ADME | Drug metabolism in cynomolgus monkey plasma assessed as formation of glucuronide metabolite at 10 mg/kg, po as single bolus dose measured after 1 to 24 hrs post dose | Macaca fascicularis | 1 | ALA3352753 | organism-based format | Scientific Literature |