| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3387261 | Functional | Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production incubated for 15 to 60 mins before I-BOP addition by HTRF assay | Homo sapiens | 13 | ALA3351871 | cell-based format | Scientific Literature | |
| 2. | ALA3387262 | Functional | Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM incubated for 15 to 60 mins before I-BOP addition by HTRF assay | Homo sapiens | 4 | ALA3351871 | cell-based format | Scientific Literature | |
| 3. | ALA3387264 | Functional | Irreversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM incubated for 15 to 60 mins before I-BOP addition and measured after 4 consecutive drug washout by HTRF assay | Homo sapiens | 2 | ALA3351871 | cell-based format | Scientific Literature | |
| 4. | ALA3387266 | Functional | Irreversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM incubated for 15 to 60 mins before I-BOP addition and measured after 6 consecutive drug washout by HTRF assay | Homo sapiens | 5 | ALA3351871 | cell-based format | Scientific Literature | |
| 5. | ALA3387267 | Functional | Irreversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM at 4 degC incubated for 15 to 60 mins before I-BOP addition and measured after 6 consecutive drug washout by HTRF assay | Homo sapiens | 1 | ALA3351871 | cell-based format | Scientific Literature | |
| 6. | ALA3387269 | ADME | Stability in CD1 mouse plasma at 1 uM after 1 hr at 37 degC by UPLC-ESI-MS/MS method | Mus musculus | 1 | ALA3351871 | cell-free format | Scientific Literature | |
| 7. | ALA3387270 | Functional | Antagonist activity against human EP1 receptor expressed in QBI-HEK293A cells assessed as reduction in 17-PGE2-induced inositol monophosphate production at 1 uM incubated for 15 to 60 mins before I-17-PGE2 addition by HTRF assay | Homo sapiens | 1 | ALA3351871 | cell-based format | Scientific Literature |
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