# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3389504 | Binding | Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry relative to AITC | Rattus norvegicus | 39 | ALA3352014 | cell-based format | Scientific Literature | |
2. | ALA3389505 | Binding | Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry | Rattus norvegicus | 39 | ALA3352014 | cell-based format | Scientific Literature | |
3. | ALA3389506 | Binding | Antagonist activity against rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry | Rattus norvegicus | 39 | ALA3352014 | cell-based format | Scientific Literature | |
4. | ALA3389507 | Binding | Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry relative to ionomycin | Rattus norvegicus | 39 | ALA3352014 | cell-based format | Scientific Literature | |
5. | ALA3389508 | Binding | Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry | Rattus norvegicus | 39 | ALA3352014 | cell-based format | Scientific Literature | |
6. | ALA3389509 | Binding | Antagonist activity against rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry | Rattus norvegicus | 39 | ALA3352014 | cell-based format | Scientific Literature | |
7. | ALA3389510 | Binding | Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry relative to ionomycin | Homo sapiens | 39 | ALA3352014 | cell-based format | Scientific Literature | |
8. | ALA3389511 | Binding | Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry | Homo sapiens | 39 | ALA3352014 | cell-based format | Scientific Literature | |
9. | ALA3389512 | Binding | Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry | Homo sapiens | 39 | ALA3352014 | cell-based format | Scientific Literature | |
10. | ALA3389514 | Binding | Selectivity index, ratio of EC50 for rat TRPM8 to EC50 for rat TRPA1 | Rattus norvegicus | 10 | ALA3352014 | assay format | Scientific Literature | |
11. | ALA3389515 | Binding | Selectivity index, ratio of EC50 for human TRPV1 to EC50 for rat TRPA1 | 10 | ALA3352014 | assay format | Scientific Literature |