| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3389531 | B | Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysis | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 2. | ALA3390066 | B | Selectivity for GST-tagged full-length ITK (unknown origin) over His-tagged LCK (unknown origin) | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 3. | ALA3390067 | B | Inhibition of PLC gamma-1 phosphorylation in human Jurkat T cells after 30 mins | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA3390068 | P | Kinetic aqueous solubility of the compound | 15 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA3390069 | A | Clearance in human liver microsomes | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA3390070 | A | Inhibition of CYP2C9 (unknown origin) at <8 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3390071 | A | Inhibition of CYP2C19 (unknown origin) at <8 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3390072 | A | Inhibition of CYP2D6 (unknown origin) at <8 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3390073 | A | Inhibition of CYP3A4 (unknown origin) at <8 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3390074 | A | Apparent permeability from apical to basolateral side in MDCK cells over expressing MDR1 | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3390075 | A | Apparent permeability from basolateral to apical side in MDCK cells over expressing MDR1 | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3390076 | A | Efflux ratio of permeability from basolateral to apical over apical to basolateral side of MDCK cells over expressing MDR1 | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3390077 | B | Inhibition of CDK2 (unknown origin) at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA3390078 | B | Inhibition of FLT3 (unknown origin) at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3390079 | B | Inhibition of MuSK (unknown origin) at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!